PURPOSE To determine whether various novel amphipathic polymers could be used to stabilize the tear film of the rat. The rheologic properties of these polymers were examined to investigate whether particular structural or physical characteristics improve the stability of the tear film. METHODS Amphipathic polymers or particular phospholipids were mixed with a test solution of tears and saline...

Objective(s): Evaluate the effect of topical antiglaucoma drugs on tear film and determine the time taken to develop symptoms and or signs of dry eye in diagnosed open angle glaucoma patients by Schirmer's test I, Schirmer's test II, Tear film break up time. Method(s): This prospective study was carried out in 60 patients attending Ophthalmology outdoor with newly diagnosed patients of primary ...

PURPOSE The purpose of this study was to examine the optical and visual impact of tear break-up. METHODS Optical quality of the eye was assessed during periods of nonblinking by quantifying vessel contrast in the fundus image and by monitoring the psychophysical contrast sensitivity and the spatial distribution of tear thickness changes by retroillumination. All measures were obtained from th...

PURPOSE To evaluate changes in the tear meniscus area and tear meniscus height over time in patients with dry eye syndrome, using anterior segment spectral-domain optical coherence tomography after the instillation of 3% diquafosol ophthalmic solution. METHODS Sixty eyes from 30 patients with mild to moderate dry eye syndrome were included. Tear meniscus images acquired by anterior segment sp...

Schirmer's test and tear film break-up time (BUT) were studied in 56 eyes of patients with pterygium and compared with 50 eyes of normal healthy subjects representing the same age, sex and geographical distribution. Both the values were found to be significantly reduced in cases of pterygium indicating the inadequacy of tear film in these patients.

purpose : the main ocular manifestation of rheumatoid arthritis is dry eye. lacritin is a secreted glycoprotein of tear and when applied topically in rabbits, it increased the volume of basal tear secretion. so the aim of this study was to compare lacritin level in rheumatoid arthritis (ra) and control group. methods : this cross-sectional study was done on 40 patients with ra and 48 healthy su...