Introduction. Fibroblast growth factor 2 (FGF2) is a potent mitogenic factor of cortical fibroblasts and induces kidney fibrosis. We hypothesized that serum levels of FGF2 has an association with the severity of vesicoureteral reflux (VUR) and renal parenchymal scar. Materials and Methods. Between 2007 and 2009, a total of 28 children with VUR were enrolled in this study and were compared with ...

the correlation of vesicoureteral reflux (vur), urinary tract infection (uti) and renal scarring is well known. several risk factors for renal parenchymal lesions have been reported previously. we determine the incidence of renal parenchymal damage and outcome in the siblings of children with primary vur. a total of 96 siblings of patients with vur, were evaluated with direct voiding cystograph...

PURPOSE This study assessed whether (99m)technetium dimercaptosuccinic acid (DMSA) scintigraphy used for the assessment of renal sequelae after febrile urinary tract infection (UTI) has any prognostic value for outcome measurement of vesicoureteral reflux (VUR) by retrospectively evaluating the correlation between abnormal DMSA scintigraphy results and persistence of VUR in children with febril...

UNLABELLED Renal length measurements are used in evaluating several abnormalities of the pediatric genitourinary tract. This study assesses reproducibility of renal length measurements obtained with 99mTc-dimercaptosuccinic acid (DMSA) SPECT. METHODS The lengths of 98 kidneys of 51 children (age range, 1-16 y; mean age, 5.4 y) who underwent 99mTc-DMSA SPECT were measured independently by 2 ob...

Tc-99m dimercaptosuccinic acid (DMSA) is used as a renal cortical imaging agent to detect parenchymal abnormalities especially in children. Kidney uptake of DMSA provides an index for evaluation of a functional tubular mass, which depends on the renal blood flow and proximal tubular cell membrane transport function. We here report a boy with renal tubular acidosis, which has noticeably reduced ...

The authors present a case of subhyoid ectopic thyroid with mediolateral location diagnosed by technetium-99m pertechnetate scan. The ectopia was associated with hypothyroidism and developmental retardation.

UNLABELLED Technetium-99m dimercaptosuccinic acid (Tc-99m DMSA) as a static renal agent is currently the most frequently used agent in the detection of renal scarring, and allows accurate calculation of differential renal function (DRF). But this agent has some disadvantages such as relatively higher radiation dose and time consumption. METHODS The purpose of this study was to evaluate the po...

Urinary tract infections are common in children. The available gold standard method for diagnosis, Tc-99m dimercaptosuccinic acid scan is expensive and exposes patients to considerable amount of radiation. This study was performed to compare and assess the efficacy of Power Doppler Ultrasound versus Tc-99m DMSA scan for diagnosis of acute pyelonephritis. A quasi experimental study was conducted...

the high expression of somatostatin receptors in many tumours, have made receptor scintigraphy with 111in-dtpa-octreotide a widly used procedure in nuclear medicine. despite its clinical success, some limitation and drawbacks of radiolabelling with 111in remain, especially those concerned with the cost, availability and physical decay properties of this radionuclide. 99mtc-edda/hynic-tyr3-toc w...

From the Departments of Pediatrics (A.H., R.W.H., E.R.W.) and Radiology (M.C.), University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh, Pittsburgh; the Department of Pediatrics, Ohio State University and Columbus Children’s Hospital, Columbus (R.W.H.); the Department of Pediatrics, Harvard Medical School and Children’s Hospital, Boston (M.B.); and the Division of Gene...