نتایج جستجو برای: tetracyclines
تعداد نتایج: 1364 فیلتر نتایج به سال:
Recent reports have shown that antibiotics such as macrolide, aminoglycoside, and tetracyclines have immunomodulatory effects in addition to essential antibiotic effects. These agents may have important effects on the regulation of cytokine and chemokine production. However, the precise mechanism is unknown. This time, we used Multi Plex to measure the production of cytokines and chemokines fol...
Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [erm(A), erm(B), and mef(A/E)] and tetracyclines [tet(M), tet(O), tet(K), and tet(L)] in streptococci.
BACKGROUND Data on more than a decade of outpatient use of tetracyclines, sulphonamides and trimethoprim, and other antibacterials in Europe were collected from 33 countries as part of the European Surveillance of Antimicrobial Consumption (ESAC) project, funded by the European Centre for Disease Prevention and Control (ECDC). METHODS For the period 1997-2009, data on outpatient use of system...
RAMSEY, CAROLYN H. (U. S. Public Health Service, Atlanta, Ga.), AND P. R. EDWARDS. Resistance of salmonellae isolated in 1959 and 1960 to tetracyclines and chloramphenicol. Appl. Microbiol. 9:389-391. 1961.-The resistance of cultures of Salmonella typhimurium to tetracyclines and chloramphenicol has been examined periodically. Although none of 200 cultures isolated prior to 1948 was resistant t...
Here we describe chemical innovations that enable the preparation of fully synthetic tetracyclines containing an all-carbon quaternary, stereogenic center at position C5a, a structurally novel class of compounds in this important family of therapeutic agents. In the key transformation and an important extension of the powerful Michael-Claisen cyclization (AB plus D) approach to the construction...
BackgroundTetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line in current hidradenitis suppurativa guidelines. However, evidence for their efficacy is drawn from small studies, often without validated outcomes.ObjectiveTo assess the 12-week of oral tetracyclines a rifampicin.MethodsA prospective, international cohort study performed between October 20...
Prion diseases are transmissible neurodegenerative disorders of humans and animals for which no effective treatment is available. Conformationally altered, protease-resistant forms of the prion protein (PrP) termed PrP(Sc) are critical for disease transmissibility and pathogenesis, thus representing a primary target for therapeutic strategies. Based on previous findings that tetracyclines rever...
Inhibition of calcification in embryonic bone rudiments was studied in the presence of several tetracyclines at three different concentrations. Different criteria for calcification and different concentrations of tetracyclines yielded parallel results and showed significant differences in the inhibitory action of the various compounds. The clear-cut results indicate that the test-system that wa...
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