OBJECTIVES To study coronary artery disease (CAD) risk factors predicting positive thallium-201 single photon emission computed tomography (SPECT) indicating underlying CAD among patients of end stage renal disease. PLACE AND DESIGN: This cross-sectional (analytical) study was done at Department of Cardiology, Punjab Institute of Cardiology, from April 2004 to Dec 2007. METHODS One hundred co...

Background. Because thallium reinjection enhances the identification of viable myocardium, many laboratories have adopted the routine practice of performing reinjection imaging instead of 3-4-hour redistribution imaging. This approach assumes that the stress-reinjection protocol provides the necessary information regarding both exercise-induced ischemia and myocardial viability. Because apparen...

Background. Thallium reinjection immediately after stress-redistribution imaging identifies ischemic but viable myocardium in as many as 50%o of the regions characterized by conventional redistribution imaging as irreversibly injured. However, we have previously shown that some regions in which irreversible defects persist despite reinjection are metabolically active, and hence viable, by posit...

OBJECTIVE To determine the sensitivity and specificity of thallium scintigraphy in detection of coronary artery disease in diabetic patients. STUDY DESIGN Cross-sectional validation study. PLACE AND DURATION OF STUDY The study was carried out from July to December 2007 in the Cardiology Department of the Pakistan Institute of Medical Sciences, Islamabad. METHODOLOGY A total of 60 diabetic...

Thallium is widely found in nature, but the only inorganic stones full of this element are crookesite and lorandit. It isalso found in pyrites of copper, lead and inorganic stones. The element and its compositions are toxic and harmful to theenvironment; therefore, its application requires caution and further research. It is important to develop sensitive andaccurate analytical methods to deter...

Serial myocardial imaging after a single dose of thallium is often used in evaluating patients with coronary artery disease. Because the appearance of the image is related to myocardial thallium content, it is important to know if transient ischemia occurring after tracer administration will influence the rate of myocardial thallium clearance. To answer this question 13 mongrel dogs (eight stud...

BACKGROUND The clinical significance and pathophysiological mechanisms of reverse redistribution on stress-redistribution thallium-201 myocardial scintigraphy in patients with chronic coronary artery disease are unclear. Recent studies have shown that thallium-201 reinjection is a useful technique for the detection of myocardial viability in chronic coronary artery disease. In this investigatio...

Serial myocardial imaging after a single dose of thallium is often used in evaluating patients with coronary artery disease. Because the appearance of the image is related to myocardial thallium content, it is important to know if transient ischemia occurring after tracer administration will influence the rate of myocardial thallium clearance. To answer this question 13 mongrel dogs (eight stud...

backgrounds: thallium-201 is produced through 203tl (p, 3n) 201pb 201tl reaction by cyclotron. this radioisotope has known as one of the cyclotron radioisotopes which is used for myocardial perfusion in the coronary artery disease, tl-201 after chemical purification and quality control in the form of 201tl-chlorid is ready to send to the hospitals. materials and methods: in this work the effect...

Thallium is a highly toxic metal and predominantly hosted by sulfides associated with low-temperature hydrothermal mineralization. Weathering oxidation of generate acid drainage high concentration thallium, posing threat to surrounding environments. may also be incorporated into secondary sulfate minerals, which act as temporary storage for thallium. We present state-of-the-art review on the fo...