The 205-316 C-terminal fragment of thermolysin has been studied by differential scanning calorimetry at pH values 2.5, 3.0, 3.5, 4.0 and 5.0 and at a constant ionic strength of 130 mM. The thermal unfolding of the fragment occurs at thermodynamic equilibrium under our experimental conditions. The effect of sample concentration at the different pH values on the calorimetric traces is consistent ...

Modeling atmospheric aerosols containing a large organic fraction with unknown chemical composition and properties has been a constant challenge. The dissertation focuses on the theoretical treatment of the thermodynamic equilibrium of atmospheric aerosol involving organic species. We present a vapor pressure estimation method, based on quantum chemistry methods, to predict the liquid vapor pre...

2 Thermodynamics 4 2.1 The Foundations of Thermodynamics . . . . . . . . . . . . . . . 4 2.2 Thermodynamic Equilibrium . . . . . . . . . . . . . . . . . . . . 5 2.3 The Conditions for Equilibrium . . . . . . . . . . . . . . . . . . . 7 2.4 The Equations of State . . . . . . . . . . . . . . . . . . . . . . . . 13 2.5 Thermodynamic Processes . . . . . . . . . . . . . . . . . . . . . . 14 2.6 Ther...

Biomolecular interactions may be defined at several levels. The simplest quantitative descriptor, affinity, is defined by the affinity constant, KD, a measure of the strength of binding at equilibrium. This term may be further resolved into kinetic descriptors of rate of association (defined by the association rate constant (ka) and dissociation (kd). Kinetic information, however, does not reve...

in this work, we have studied the solvent effects on values of gibbs free energy, enthalpy. entropy and dipolemoment in spread of solvents around anticancer thug of temreolomide that is an alighting agent. for thispurpose, the quantum mechanic calculations bawd on hanrertnick theory at the sto-36/3-2ith levels havebeen done. moreover, we have compared resulted thermodynamic values in gas phase ...

Thermodynamic length is a metric distance between equilibrium thermodynamic states. Among other interesting properties, this metric asymptotically bounds the dissipation induced by a finite time transformation of a thermodynamic system. It is also connected to the Jensen-Shannon divergence, Fisher information, and Rao's entropy differential metric. Therefore, thermodynamic length is of central ...

The general thermodynamic analysis of the quantum vacuum, which is based on our knowledge of the vacua in condensed-matter systems, is consistent with the Einstein earlier view on the cosmological constant. In the equilibrium Universes the value of the cosmological constant is regulated by matter. In the empty Universe, the vacuum energy is exactly zero, λ = 0. The huge contribution of the zero...

The general thermodynamic analysis of the quantum vacuum, which is based on our knowledge of the vacua in condensed-matter systems, is consistent with the Einstein earlier view on the cosmological constant. In the equilibrium Universes the value of the cosmological constant is regulated by matter. In the empty Universe, the vacuum energy is exactly zero, λ = 0. The huge contribution of the zero...

The response of ecosystems to perturbations is considered from a thermodynamic perspective by acknowledging that, as for all macroscopic systems and processes, the dynamics and stability of ecosystems is subject to definite thermodynamic law. For open ecosystems, exchanging energy, work, and mass with the environment, the thermodynamic criteria come from non-equilibrium or irreversible thermody...