Thermoresponsive bilayer hydrogels have gained attention due to their fast response time and excellent recovery. A side-by-side capillary-based microfluidic device has been used produce thermoresponsive Janus fibers by photopolymerization of monomer streams. These had one parts consisting in a polymer obtained from oligo(ethylene glycol) acrylate, 2-ethoxyethyl poly(ethylene diacrylate, while t...

This data article contains two figures and one table supporting the research article entitled: "Continuous harvest of stem cells via partial detachment from thermoresponsive nanobrush surface" [1]. The table shows coating conditions of three copolymers, poly(styrene-co-acrylic acid) grafted with oligovitronectin, poly(styrene-co-N-isopropylacrylamide) and poly(styrene-co-polyethylene glycol met...

Thermoresponsive gelling materials constructed from natural and synthetic polymers can be used to provide triggered action and therefore customised products such as drug delivery and regenerative medicine types as well as for other industries. Some materials give Arrhenius-type viscosity changes based on coil to globule transitions. Others produce more counterintuitive responses to temperature ...

"Smart" hydrogels are part of an emerging class of biomaterials that respond to multiple external stimuli. A range of thermoresponsive magnetic hydrogels is currently being developed for on-demand delivery of biomolecules for a range of biomedical applications, including therapeutic drug delivery, bioimaging, and regenerative engineering. In this review article, we explore different types of ma...

SCK nanoparticles having differing core thermal characteristics were designed and evaluated as thermoresponsive drug delivery systems of doxorubicin for the killing of cancerous cells.

PURPOSE To characterize thermoresponsive hydrogels (liquids at room temperature, gels at body temperature) as a novel drug delivery platform to the posterior segment. METHODS Thermoresponsive hydrogels were synthesized using poly(N-isopropylacrylamide) (PNIPAAm), cross-linked with poly(ethylene glycol) diacrylate (PEG-DA). Proteins were then encapsulated into the hydrogels, including bovine s...

A combination of temperature and concentration gradient microfluidic devices were employed to study the mechanistic details of biomacromolecule interactions at oxide interfaces. These lab-on-a-chip techniques allowed high-throughput, multiplexed data collection using only nanoliters of analyte. The three examples presented demonstrate rapid data acquisition relative to standard methods. First, ...

This paper describes the effects of graft architecture of poly(N-isopropylacrylamide) (PIPAAm) brush surfaces on thermoresponsive aqueous wettability changes and the temperature-dependent hydrophobic interaction of steroids in silica capillaries (I.D.: 50 μm). PIPAAm brushes were grafted onto glass substrates by surface-initiated atom transfer radical polymerization (ATRP) that is one of the li...

This study describes a facile two-step approach to modify the surface of nanoparticles, thereby imparting a core-shell structure to the system. The core consists of magnetic nanoparticles and the shell is composed of thermoresponsive hydroxypropyl cellulose, using a coupling agent to covalently bind the core to the shell. Hydroxypropyl cellulose is known for its biocompatibility and biodegradab...