Juvenile retinoschisis (RS) is an X linked recessive vitreoretinal disorder for which the basic molecular defect is unknown. The gene for RS has been previously localised by linkage analysis to Xp22.1-p22.2 and the locus order Xpter-DXS16-(DXS43, DXS207)-RS-DXS274-DXS41-Xcen established. To improve the resolution of the genetic map in the RS region, we have isolated a highly polymorphic microsa...

Since the discovery of place cells - single pyramidal neurons that encode spatial location - it has been hypothesized that the hippocampus may act as a cognitive map of known environments. This putative function has been extensively modeled using auto-associative networks, which utilize rate-coded synaptic plasticity rules in order to generate strong bi-directional connections between concurren...

We study the differential equations governing mirror symmetry of elliptic curves, and obtain a characterization of the ODEs which give rise to the integral q-expansion of mirror maps. Through theta function representation of the defining equation, we express the mirror correspondence in terms of theta constants. By investigating the elliptic curves in X9-family, the identification of the Landau...

Accomplishing even simple tasks depend on neuronal circuits to configure how incoming sensory stimuli map onto responses. Controlling these stimulus-response (SR) mapping rules relies on a cognitive control network comprising the anterior cingulate cortex (ACC). Single neurons within the ACC convey information about currently relevant SR mapping rules and signal unexpected action outcomes, whic...

Dirac fermions in $2+1$ dimensions with dynamically generated anticommuting SO(3) antiferromagnetic (AFM) and Z$_2$ Kekul\'e valence-bond solid (KVBS) masses map onto a field theory topological $\theta$-term. This term provides mechanism for continuous phase transitions between different symmetry-broken states: defects of one carry the charge other proliferate at transition. The $\theta$-term i...

In this paper, we construct cataclysm deformations for $\theta$-Anosov representations into a semisimple non-compact connected real Lie group $G$ with finite center, where $\theta \subset \Delta$ is subset of the simple roots that invariant under opposition involution. These generalize Thurston's cataclysms on Teichm\"uller space and Dreyer's Borel-Anosov $\mathrm{PSL}(n, \mathbb{R})$. We expre...

Genetic linkage studies were performed in 16 British families affected by X linked ocular albinism (XLOA) using RFLPs from the Xp22.3 region. Linkage was confirmed between the XLOA locus (OA1) and the loci DXS143 (dic56; Zmax = 15.90 at theta = 0.0, confidence interval (CI) 0-0.035), DXS85 (782; Zmax = 15.67 at theta = 0.04, CI = 0.007-0.11), and DXS237 (GMGX9; Zmax = 12.65 at theta = 0.08, CI ...

Inherited cataract is a clinically and genetically heterogeneous disease. Here we report the identification of a new locus for an autosomal dominant anterior polar cataract on the short arm of chromosome 17. To map this new locus we performed genetic linkage analysis with microsatellite markers in a four-generation pedigree. After exclusion of seven candidate loci for cataract, we obtained sign...

Neural networks underlying visual perception exhibit oscillations at different frequencies (e.g.,). But how these map onto distinct aspects of visual perception remains elusive. Recent electroencephalography data indicate that theta or beta frequencies at parietal sensors increase in amplitude when conscious perception is dominated by global or local features, respectively, of a reversible visu...

objective: in this research, a new approach termed as “evolutionary-based brain map” is presented as a diagnostic tool to classify schizophrenic and control subjects by distinguishing their electroencephalogram (eeg) features. methods: particle swarm optimization (pso) is employed to find discriminative frequency bands from different eeg channels. by deploying the energy of those selected frequ...