HAVE INSTITUTED a colorimetric chloride procedure which has been in use for 3 years in our laboratory and has met with great success. This colorimetric method is based on a procedure used in automated syStems* (2, 3). It is extremely simple, quite accurate, and gives highly reproducible results even in the hands of student technicians. Those laboratories not having access to a chloridometer or ...

Two rapid, simple and sensitive extractive specrophotometric methods has been developed for the assay of Hyoscine butyle bromide (HBB), losartan potassium (LSR) and Sertaline HCl (SER) in bulk and in their pharmaceutical formulations. The proposed methods depend upon the reaction of cobalt(II)–thiocyanate (method A) and molybdenum(V)–thiocyanate ions (method B) with the cited drugs to form stab...

BACKGROUND Perchlorate and thiocyanate interfere with iodide uptake at the sodium-iodide symporter and are potential disruptors of thyroid hormone synthesis. Perchlorate is a common contaminant of water, food, and human milk. Although it is known that iodide undergoes significant diurnal variations in serum and urinary excretion, less is known about diurnal variations of milk iodide levels. O...

Measurement of intracellular potassium activity (ak) is important in furthering our understanding of the basis of the low resting and maximum diastolic potentials and the membrane currents underlying pacemaker activity in the sinoatrial node. K-selective microelectrodes have been successfully applied to measure ak in Purkinje fibers, ventricular muscle, and atrium. Similar measurements in the s...

The potential risks in the use of thiocyanate salt for the activation of the Lactoperoxidase System (LPs) have been strongly discussed at international level. This study approaches different factors associated to variations of the thiocyanate ion concentrations in milk under the tropic conditions. Mean thiocyanate concentrations in bulk milk are between 0,10-0,15 mmol/liter, with a general mean...

Complex formation of 1,6-anhydro-β-maltose and sodium ions was characterized using single-crystal X-ray crystallography and solutionand solid-state NMR spectroscopy. The 7-coordination structure, comprising two 1,6-anhydroβ-maltoses, a thiocyanate ion and a sodium ion, was identified in the crystal of the complex, where a sodium ion was positioned in the center of the pentagon. In the NMR study...

Temperature-dependent yellow-to-red colour changes of uranyl thiocyanate complexes with 1-alkyl-3-methylimidazolium cations have been studied by different spectroscopic methods and this phenomenon is attributed to changes in the local environment of the uranyl ion, including the coordination number, as well as to cation-anion interactions.

Simple, rapid and sensitive spectrophotometric methods were developed for the determination of chlorodiazepoxide drugs in pharmaceutical dosage forms. This method is based on ion pair and charge transfer complexation reactions. The method is based on the reaction of the chlorodiazepoxide drug with Mo(V)–thiocyanate in hydrochloric acid medium followed by an extraction of the coloured ion-pair w...

A highly selective poly(vinyl chloride) (PVC) membrane electrode based on an N,N'-ethylene-bis(4-methyl-salicylidineiminato) nickel(II) [Ni(EBMSI)] complex as a carrier for a thiocyanate-selective electrode is reported. The influences of the membrane composition, pH and possible interfering anions were investigated based on the response properties of the electrode. The electrode exhibited a goo...