an environmentally benign and clean synthesis of aryl-hydrazones by reacting variety of carbonyl compounds with thiosemicarbazide, semicarbazide, aminoguanidine, and phenyl hydrazine has been achieved using aqueous extract of acacia concinna pods as a natural surfactant type catalyst. we found that the aqueous extract of acacia concinna pods could be effectively used for the synthesis of aryl-h...

some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. the reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. all the synthesized compounds were characterized by their physical and spectral data.

This investigation involved the synthesis of metal complexes to test the hypothesis that structural changesand metal coordination in pyridine thiosemicarbazones affect cell growth and cell proliferation in vitro. Thiosemicarbazones are well known to possess antitumor, antiviral, antibacterial, antimalarial, and other activities. Extensive research has been carried out on aliphatic, aromatic, he...

Chemical modification of CS and its derivatives can enhance their properties and consequently expands their potential applications. And because of this, CS and its derivatives have been used in a number of different fields nowadays. They are an important class of N, S donor ligands which attract considerable interest because of their chemistry and biological activities, such as antitumor, antib...

Six new fluorinated thiosemicarbazones R‑C(R')=N-NH-C(S)NH(2) (R = 2,4-C(6)H(3)F(2), R' = H (1); R = 2,5-C(6)H(3)F(2), R' = H (2); R = 2,6-C(6)H(3)F(2), R' = H (3); R = 3,4-C(6)H(3)F(2), R' = H (4); R = 3,5-C(6)H(3)F(2), R' = H (5) and R = 4-C(6)H(4)F, R' = C(6)H(5), (6)) have been prepared. The molecular structures of compounds 1 to 6 have been determined.

Some new Thiosemicarbazones containing Benzimidazole moiety were synthesized by combination of conventional as well as green chemistry methods, which had potential Anti – tumor activity against various cancerous cells. All the compounds were submitted to National Cancer Institute, USA for in vitro anti-cancer screening against 60 human cancer cell lines. Our one compound S2 (NSC 92491) was sele...

In screening for anonymous mycobacteria the use of thiosemicarbazone (10mug./ml.) may give rise to false positive results. Although these can usually be overcome by further tests, additional time and effort is required, which seriously limits the value of thiosemicarbazone as a true screening agent. Para-nitrobenzoic acid (500 mug./ml.) has proved more satisfactory in our hands; no false positi...