While the effect of changes of stimulus waveform (quasitrapezoidal and rectangular current pulses) on nerve activation is clear, but there is no evidence on the effect of quasitrapezoidal pulses on ionic currents of cellular membrane. In the present study, the effect of depolarizing quasi-trapezoidal current pulses, in comparison with that of depolarizing rectangular current pulses, on firing...

there is strong evidence demonstrating that nifedipine dissolved in ethanol selectively inhibits only l-type ca2+ current. in addition, acute ethanol exposure reduces voltage-dependent calcium currents. in the present study, we investigated the antagonistic effect of fixed concentration of nifedipine dissolved in different concentration of ethanol on l-type ca2+ current. in a na+-k+ free soluti...