Thymomas and thymic carcinomas are rare mediastinal neoplasms arising from epithelial cells, the presence of synchronous or metachronous primary in a single patient is an extremely event. Thymoma patients appear to have inherent predisposition toward developing additional neoplasms. This additionally presents diagnostic challenge, revealing importance multidisciplinary expertise management thes...

Malignant thymoma is an extremely rare entity. According to a study, the annual incidence of malignant thymoma was estimated to be 0.15 per 100,000 person-years. We present the case of a 42-year-old female who came to us with a Type AB, Masaoka stage III malignant (invasive) thymoma with widespread involvement of the mediastinum.

Thymoma is a common anterior mediastinal mass, although thymomas have occasionally been found in the neck, pulmonary hillus, or posterior mediastinum. But a thymoma within the middle mediastinum has rarely been reported. We report a thymoma arising in the middle mediastinum with a review of the literature.

Ectopic pleural thymoma is a rare entity.In this paper, we present the case of ectopic discovered in patient with COVID-19.
 A 49-year-old man COVID-19 pneumonia who had constant right mass during her hospitalization that was finally diagnosed as thymoma.
 complete surgical resection achieved after recovery from and postoperative diagnosis WHO type AB, modified Masaoka stage I tumor a...

mediastinal neoplasms are uncommon tumors that can occur at any age but are most common through the fifth decades of life. a wide variety of systemic disorders are associated with 71% of thymomas. the symptoms of these as sociated disorders often lead to the original discovery of the mediastinal tumor. a 35-year-old female with petechia and purpura was admitted to sina hospital of the city of h...

Objective: There have been con ̄icts concerning the criteria for diagnosing malignant epithelial neoplasms of thymic origin. To differentiate thymic carcinomas from thymomas, the maturation stage of T-lineage lymphoid cells in®ltrating thymomas and thymic carcinomas was examined by ̄ow cytometry to associate it with the degree of tumor malignancy. Methods: Multidimensional ̄ow cytometric analysi...

A 38-year-old Japanese male was referred to our hospital with abnormal chest X-ray results and severe Coombs-positive hemolytic anemia. He was diagnosed with a stage IV, WHO type A thymoma and was treated with oral prednisolone (1 mg/kg/day) and subsequent chemotherapy. After chemotherapy, the patient underwent surgical resection of the thymoma. Hemolysis rapidly disappeared and did not return ...

Thymoma represents <1% of all mediastinal tumors in children. Less than 50 cases of pediatric thymoma are reported in the literature. Thymomas are considered to be highly aggressive in pediatric patients, especially when age is <10 years. Paraneoplastic syndromes, of which around 70% are myasthenia gravis, correlate with poor prognosis. In this article, we report a case of a thymoma in an 8-yea...

Myasthenia gravis is an archetypal human autoimmune disease. Thymectomy proven effective by controlled clinical trials, and commonly part of the immunotherapeutic approach when myasthenia creates generalized weakness. Pemphigus foliaceus also but treated medically; thymectomy not therapy unless thymoma discovered. Autoimmune mechanisms, age distribution, response to in disorders are likely be d...

Aplastic anemia is a rare complication of thymoma and is extremely infrequent after thymectomy. We present a case of a 60-year-old woman with very severe aplastic anemia appearing sixteen months after thymectomy for a thymoma. She underwent thymectomy for a thymoma in April 2000. Preoperative examination revealed no hematologic abnormality. About sixteen months after the operation, she was read...