Impaired glucose tolerance creates a peripheral nervous system that is susceptible to chronic nerve compression. While it is accepted that surgical decompression of the median nerve at the wrist, for carpal tunnel syndrome, is appropriate in the diabetic, application of this concept to the lower extremity has not yet gained widespread recognition. Traditional electrodiagnostic studies demonstra...

BACKGROUND Traditional tibial nerve stimulation (TNS) has been used to treat overactive bladder syndrome (OAB), but there are some shortcomings. Thus, a novel alternative is needed for the treatment of OAB. The study investigated the effects of a new type of tibial nerve microstimulator on the micturition reflex in cats. METHODS An implantable wireless driver microstimulator was implanted aro...

The purpose of this study was to evaluate the inter-hamstring position (medial to lateral intertendinous position) of the tibial nerve within the popliteal fossa. A descriptive cadaver model study was performed to permit controlled and direct measures of the tibial nerve. Fourteen embalmed lower extremities (8 left, 6 right) from nine cadavers (4 males, 5 females; 84.3 +/- 10.7 years of age) we...

OBJECTIVE To compare nerve conduction parameters in asymptomatic diabetic patients and with no clinical signs of neuropathy and in control subjects. METHODS Forty-eight diabetic Saudi subjects (20 males, 28 females) and 48 age-and-sex-matched control subjects were studied. The mean age of patients +/- standard deviation was 45.6+/-11.7 years. The mean duration of diabetes from time of diagnos...

The tibial nerve transection model is a well-tolerated, validated, and reproducible model of denervation-induced skeletal muscle atrophy in rodents. Although originally developed and used extensively in the rat due to its larger size, the tibial nerve in mice is big enough that it can be easily manipulated with either crush or transection, leaving the peroneal and sural nerve branches of the sc...

The etymology of anatomical terminology provides insight into the history anatomy, medicine, and scientific understanding. Therefore, this study assessed language 7th century Codex Amiatinus, earliest surviving most reliable copy Saint Jerome’s original 4th Latin Vulgate translation Bible, for details regarding injury Jacob as described in Book Genesis 32:22-32. Amiatinus notes that sustained a...

PURPOSE The Overactive Bladder Innovative Therapy Trial during phase 1 was a randomized trial demonstrating comparable effectiveness of percutaneous tibial nerve stimulation and extended-release tolterodine during 12 weeks of therapy for frequency, nocturia, urgency, voided volume and urge incontinence episodes. In this second phase of the Overactive Bladder Innovative Therapy Trial we assessed...

INTRODUCTION Peripheral nerve injuries are encountered frequently in clinical practice. In nerve repair, an end-to-end suture is the preferable choice of treatment. However, where primary closure is not possible, the defect is to be repaired with a nerve graft. METHODS A total of 21 female Wistar rats weighing 230 to 290 g were used in the study. They were classified into the following 3 grou...

OBJECTIVE Establishing reference values for neuroconduction studies regarding the peroneal, tibial and sural nerves in a group of young adults. MATERIALS AND METHODS Neuroconduction was tested (also known as nerve conduction velocity (NCV) tests) on 155 asymptomatic subjects' tibial, peroneal and sural nerves using current conventional techniques, after informed written consent had been obtai...