While timelines for clinical development have been extensively studied, there is little data on the broader path from initiation of research on novel drug targets, to approval of drugs based on this research. We examined timelines of translational science for 138 drugs and biologicals approved by the FDA from 2010-2014 using an analytical model of technology maturation. Research on targets for ...

Patch management of networks is essential to mitigate the risks from the exploitation of vulnerabilities through malware and other attacks, but by setting too rigorous a patching policy for network devices the IT security team can also create burdens for IT operations or disruptions to the business. Different patch deployment timelines could be adopted with the aim of reducing this operational ...

Real world planning applications typically involve making decisions that consumes limited resources, which requires both planning and scheduling. In this paper we propose a new approach that bridges the gap between planning and scheduling by explicitly modeling the problem in terms of resources, state variables and actions. We show that it is an intuitive way to formulate real world problems wi...

The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. journal also has a website. Free full text access available for all readers.The Lanka Child Health now indexed SciVerse Scopus (Source Record ID 19900193609), Index Medicus South-East Asia Region (IMSEAR), CABI (Centre Agriculture and Bioscience International Global Database), DOAJ Google, as well Google S...

To better organize and understand online news information, we propose Storybase1, a knowledge base for news events that builds upon Wikipedia current events and daily Web news. It first constructs stories and their timelines based on Wikipedia current events and then detects and links daily news to enrich those Wikipedia stories with more comprehensive events. We encode events and develop effic...

Consistency maintenance techniques used in networked multiplayer games require a tradeoff between the degree of consistency and the responsiveness to player commands. The choice of which technique is most appropriate depends upon the specific game situation. However, all techniques share the need to deal with time as well as with game state data. This can make implementing consistency maintenan...

This paper addresses a central sub-task of timeline creation from historical Wikipedia articles: learning from text which of the person names in a textual article should appear in a timeline on the same topic. We first process hundreds of timelines written by human experts and related Wikipedia articles to construct a corpus that can be used to evaluate systems that create history timelines fro...