Introduction: Mounting is the final stage in histologically preparing a slide and creates permanent bond between coverslip slide, preventing breakage, air drying artefacts, stain fading. Materials & methods: In this study, fifty slides were prepared, twenty-five of which mounted using DPX twenty five cyanoacrylate adhesive. The assessed for clarity nuclear cytoplasmic details, adhesion pres...

Tissue adhesives are attractive materials with potential to replace the use of sutures and staples in the repair of the injured tissues. The research field of tissue adhesives is dynamically growing, and different methods and tissue models are employed to evaluate the adhesive properties of newly developed materials. It is thus difficult to directly compare the properties of materials developed...

Suture materials and surgical knot tying techniques have improved dramatically since their first use over five millennia ago. However, the approach remains limited by the ability of the suture to transfer load to tissue at suture anchor points. Here, we predict that adhesive-coated sutures can improve mechanical load transfer beyond the range of performance of existing suture methods, thereby s...

Capturing, separation and removal of thin, evasive, and often transparent membranes attached to the underlying tissue is typically a very difficult task in vitreoretinal surgery. The most challenging part of such procedures is in initial separation of the membrane, which then allows for a strong grip of the micro-tweezers holding it from two sides. Attempts of performing this procedure often le...

We define a material pattern as a particular arrangement of material elements in space. We then make an effort to categorize the developmental strategies that underlie the emergence of multicellular patterns. These strategies are divided into three broad categories according to whether cell position influences or is influenced by cell fate. In that category of strategies in which cell fate infl...

Ramond, M-J, Valla, D., Mosnier, J-F, Degott, C., Bernau., J., Rueff, B. and Benhamou, J-P. (1989) Successful Endoscopic Obturation of Gastric Varices with Butyl Cyanoacylate. Hepatology; 10: 488-493. In 27 patients who had bled from esophagogastric varices, large-sized and/or actively bleeding gastric varices were endoscopically obturated with the tissue adhesive butyl cyanoacrylate. Active bl...

Gallic acid-functionalized materials possess superior tissue-adhesive, antioxidant, and immunomodulatory properties due to the lower pKa faster oxidation kinetics, making them dopamine derivatives for biomedical applications.

A synthetic mimic of mussel adhesive protein, dopamine-modified four-armed poly(ethylene glycol) (PEG-D4), was combined with a synthetic nanosilicate, Laponite (Na(0.7+)(Mg5.5Li0.3Si8)O20(OH)4)(0.7-)), to form an injectable naoncomposite tissue adhesive hydrogel. Incorporation of up to 2 wt % Laponite significantly reduced the cure time while enhancing the bulk mechanical and adhesive propertie...

Mussel-inspired adhesive hydrogels represent innovative candidate medical sealants or glues. In the present work, we describe an enzyme-degradable mussel-inspired adhesive hydrogel formulation, achieved by incorporating minimal elastase substrate peptide Ala-Ala into the branched poly(ethylene glycol) (PEG) macromonomer structure. The system takes advantage of neutrophil elastase expression upr...