OBJECTIVE To assess the association between the history of chronic periodontitis and the risk of tongue cancer. DESIGN Case-control study using preexisting data from patients admitted between June 15, 1999, and November 17, 2005. SETTING Department of Dentistry and Maxillofacial Prosthetics at Roswell Park Cancer Institute (RPCI), Buffalo, NY. PATIENTS The cases comprised 51 non-Hispanic ...

OBJECTIVE Treatment for oral tongue cancer poses unique challenges to restoring and maintaining personally acceptable, intelligible speech. METHODS We report how oral tongue cancer survivors describe their speech after treatment in a qualitative descriptive approach using constant comparative technique to complete a focal analysis of interview data from a larger grounded theory study of oral ...

We recently reported that the polycomb complex protein Bmi1 is a marker for lingual epithelial stem cells (LESCs), which are involved in the long-term maintenance of lingual epithelial tissue in the physiological state. However, the precise role of LESCs in generating tongue tumors and Bmi1-positive cell lineage dynamics in tongue cancers are unclear. Here, using a mouse model of chemically (4-...

INTRODUCTION This article presents the case of a 26-year-old woman with tongue cancer. The median age at the diagnosis of the tongue's cancer is 61 years. Only approximately 2% of patients are diagnosed before the age of 35. CASE PRESENTATION Our patient survived acute myeloid leukemia (AML) before her second year. She had been having recurrent, poorly healing aphtae on the right side of the ...

In general, tongue cancer is usually treated surgically and additional therapy is carried out if patients have advanced cancers. Although surgical treatment is performed at the early stage of tongue cancer, still some problems emerge, such as late cervical lymph node metastasis and elective neck dissection. We previously recommended elective neck dissection for patients with T2 tongue cancers (...

Primary tumors metastasizing to the oral cavity are extremely rare. Lung is one of the most common primary sources of metastases to the tongue. Although the incidence of lung cancer is increasing, tongue metastasis as the initial presentation of the tumor remains uncommon. Due to the rarity of tongue metastasis, little is known about its imaging findings. Herein we report the magnetic resonance...

statement of the problem : geographic tongue is characterized by loss of filliform papillae in an erythematous area with keratotic borders. it vanishes after a while and reappears in another area. it is relatively common and is most seen among females. considering such problems as pain, burning sensation and sharp pain in tongue, decreasing of taste sensation, cancer phobia and esthetic problem...

OBJECTIVE To analyse correlations between quality of life measures, aspiration and extent of surgical resection in patients who have undergone free-flap tongue reconstruction. PATIENTS AND METHODS Nine consecutive patients (seven men and two women; average age 51 years) who had been diagnosed with T4a carcinoma of the mobile tongue and/or tongue base and treated by glossectomy, free-flap reco...

OBJECTIVES Nodal metastases status among early stage tongue squamous cell cancer patients plays a decisive role in the choice of treatment, wherein about 70% patients can be spared from surgery with an accurate prediction of negative pathological lymph node status. This underscores an unmet need for prognostic biomarkers to stratify the patients who are likely to develop metastases. MATERIALS...