Low larkspurs (Delphinium nuttalliunum Pritz., Delphinium andersonii Gray) and plains larkspur (Delphinium geyeri Greene) often poison cattle grazing on western North American rangelands. The dominant toxic alkaloid in larkspur is methyllycaconitine (MLA); other very toxic alkaloids in low and plains larkspurs are nudicauline and geyerline. Toxic alkaloid concentrations in larkspur near or abov...

Objectives: Belonging to Papaveraceae family, Glaucium vitellinum is one of the Persian endemic plants which has not been investigated biologically. The present paper focused on the assessment of the antibacterial and antifungal activities of the total methanol extract and alkaloid sub-fraction of the flowering aerial parts of G. vitellinum. Materials and Methods: The antibacterial and antifung...

Development of novel synthetic methodologies and their application to synthesis of natural products are described. The first topic is about an extension of the scope of our indole synthesis by radical cyclization of o-alkenylphenyl isocyanides. By utilizing this methodology and nitrogenzenesulfonamide chemistry, an efficient total synthesis of hexacyclic aspidosperma indole alkaloid, aspidophyt...

Based on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than total alkaloids. The contact toxicity from these alkaloids against the aphid Lipaphis erysimi was ...

opium poppy (papaver somniferum l.) has two major products: alkaloids in the capsules and the seeds. it is known that opium poppy today contains alkaloid in great quantities. opiate alkaloids and their synthetic derivatives are widely used in medicines which are produced in hundreds of tons for the medicine industry. the study aimed to screen the capsules of six turkish opium poppy lines to eva...

The first total synthesis of polycyclic Stemona alkaloid maistemonine has been achieved. The efficient approach features a stereoselective intramolecular Schmidt reaction, a ketone-ester condensation, and a Reformatsky reaction. Additionally, another Stemona alkaloid stemonamide was divergently synthesized from a common intermediate.