OBJECTIVES 1) To estimate the annual cost of patients with stable chronic obstructive pulmonary disease (COPD) followed in primary care in Spain; 2) To analyze the possible cost predictor variables. PATIENTS AND METHODS A multicenter, epidemiological, observational, descriptive study. Sociodemographic data, severity of disease, associated comorbidity, treatment followed by patients, quality o...

The purpose of this paper is to extend [Ouyang, L. Y., Chuang, B. R. (2001). A periodic review inventory-control system with variable lead time. International Journal of Information and Management Sciences, 12, 1–13] periodic review inventory model with variable lead time by considering the fuzziness of expected demand shortage and backorder rate. We fuzzify the expected shortage quantity at th...

AIMS To estimate the financial cost to the NHS of infant crying and sleeping problems in the first 12 weeks of age and to assess the cost effectiveness of behavioural and educational interventions aimed at reducing infant crying and sleeping problems relative to usual services. METHODS A cost burden analysis and cost effectiveness analysis were conducted using data from the Crying Or Sleeping...

The objective of this study is to estimate the mean annual social cost per adult person and the total social cost of rheumatoid arthritis (RA) in Italy. A literature review was performed by searching primary economic studies on adults in order to collect cost data of RA in Italy in the last decade. The review results were merged with data of institutional sources for estimating - following the ...

The paper studies optimization of shell-and-tube heat exchangers using the particle swarm optimization technique. A total cost function is formulated based on initial and annual operating costs of the heat exchangers. Six variables – shell inside diameter, tube diameter, baffle spacing, baffle cut, number of tube passes and tube layouts (triangular or square) – are considered as the design para...

In this study production, reproduction, population, management and economic parameters resulted from recording of 7 flocks with size 57 to 400 and 721 heads of camels in a cycle of reproduction, during three years from 2011 to 2013 were used to find out of the economic values of important traits in one hump camel in desert areas rearing system. The economic traits that appeared in profit equati...

The present study aims at estimating the total cost of MS in Europe based on actual cost data from nine countries and published epidemiological evidence. The epidemiological data are reported as 12 months prevalence estimates and cost data calculated as annual cost per patient at given levels of disease severity. Cost data are extrapolated to the rest of Europe based on a model, using economic ...

OBJECTIVES We aimed to estimate the annual socioeconomic burden of coronary heart disease (CHD) in Korea in 2005, using the National Health Insurance (NHI) claims data. METHODS A prevalence-based, top-down, cost-of-treatment method was used to assess the direct and indirect costs of CHD (International Classification of Diseases, 10th revision codes of I20-I25), angina pectoris (I20), and myoc...

predicting the maintenance and management costs and replacement age of tractors in agricultural mechanized units, is important from several points. so, doing a timely agricultural operations, more accurate measure of the amount of income  including the cost of these items , determining the useful life of old tractors , replacement age, cost of the process changes and the possibility of examinin...