نتایج جستجو برای: total body irradiation dose homogeneity
تعداد نتایج: 1752574 فیلتر نتایج به سال:
In the first myeloma trial of the M.R.C. working party on leukaemia in adults the deaths that have occurred can be attributed to unrelated diseases (5%h-for example, cosonary thrombosis, etc.); causes indirectly telated to the tumour (80,for example, pneumonia due to the immune paresis); no obvious response of the tumour to treatment (27/); and finally relapse of the tumour after an initial res...
The effect of ionizing irradiation on testes and the protective effects of melatonin were investigated by immunohistochemical and electron microscopic methods. Eighty-two adult male Wistar rats were divided into 10 groups. The rats in the irradiated groups were exposed to a sublethal irradiation dose of 8 Gy, either to the total body or abdominopelvic region using a 60Co source at a focus of 80...
Dose homogeneity in head and neck tumour irradiation is a challenging task for conventional radiotherapy due to large anatomic contour irregularities and tissue heterogeneities in irradiation volumes. We present a simple technique based on the omni-wedge concept which uses superimposed fields, orthogonally wedged, to improve target-volumes homogeneity in head and neck tumour irradiation. The ro...
T-cell adoptive immunotherapy for stringent murine tumor models, such as intracranial, s.c., or advanced pulmonary metastases, routinely uses lymphodepletive conditioning regimens before T-cell transfer, like recent clinical protocols. In this study, we examined whether host lymphodepletion is an obligatory component of curative T-cell therapy; we also examined the mechanism by which it augment...
The intensity modulated raster scanning technique enables an extremely precise irradiation of tumours, which can be fixed in position and do not move. This thesis investigates how to extend raster scanning to moving target volumes, like in the thorax. Two different strategies were studied: A rescanning of the volume which is not correlated to the target motion and an active realignment of the b...
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