Budgerigar is a common name for a colorful Australian native bird belonging to the Melopsittacus undulatus species. It is a very familiar pet around the world and its breeding has been grown in Iran. This study was conducted on a 2-year-old budgerigar with a nodular mass on the left wing. Physical examination revealed a firm, round and well-circumscribed mass approximately 1.70 cm in d...

Necrobiotic xanthogranuloma is an uncommon granulomatous disease involving the skin and extracutaneous tissues. It is characterized by indurated, yellow-red plaques and nodules, involving primarily the face and less frequently the trunk and extremities. The disease has a strong association with paraproteinemia and other hematologic or lymphoproliferative disorders. Histologically, the dermal pa...

[b]BACKGROUND[/b] Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis characterized by foamy histiocytes, Touton-like giant cells, and fibrosis, typically affecting the diaphyseal metaphyseal region long bones but that can involve any organ or tissue. ECD usually associated with BRAF V600E mutation other molecular mutations inserted in MAPK cascade. [b]CASE REPORT[...

Juvenile xanthogranuloma is a benign histiocytic tumor predominantly occurring in children as yellowish papules on the head and trunk. Presentations on the volar surfaces are rare and may cause diagnostic confusion with pyogenic granuloma, eccrine poroma and digital fibrokeratoma. We report two patients with unusual presentations of solitary juvenile xanthogranuloma on the palm or sole. Both ha...

objective: oral lesions are among the important reasons for seeking dental care. being frequently encountered, giant cell lesions form an important group of oral lesions. the epidemiologic data on these lesions, however, is scarce in iran. the present study investigated epidemiological and demographic characteristics of giant cell lesions in oral biopsies done in one of the largest oral patholo...

Juvenile xanthogranuloma (JXG) is a benign manifestation of non-Langerhans cell histiocytosis characterized by yellowish cutaneous nodules. Its occurrence in the larynx is very rare, but laryngeal JXG may cause severe respiratory distress. We report a patient with isolated laryngeal JXG treated by laryngomicrosurgery, and this is the first report of JXG extending to vocal fold. A 3-year-old gir...

introduction: giant cell lesions of the bone comprise a group of jaw bone pathologies. different pathogeneses such as reactive, vascular or neoplastic have been proposed for these lesions. in addition, differentiating between aggressive and nonaggressive central giant cell granuloma (cgcg) of the jaws based on histopathologic features is still impossible and due to different treatment protocols...

A 51-year-old man with a history of recurrent primary cutaneous marginal zone lymphoma involving his back returned for a follow-up visit at our cutaneous lymphoma clinic. He complained of a several-month history of a new asymptomatic papule on the mid-thoracic back. He denied fevers, chills, night sweats or fatigue. Clinical examination identified a 3 to 4 mm red to orange-colored papule on the...

The purpose of this study was to describe a case of necrobiotic xanthogranuloma scleritis in a 53-year-old male with unilateral progressive visual loss, scleritis, prolonged fever, and multiple mononeuropathy. Scleral biopsy showed necrosis with small abscess, and the pathological tissues revealed submucosal infiltration of mononucleated foamy histiocytes (xanthoma cells), hemosiderin-laden mac...