The development of Grave’s ophthalmopathy following radioiodine treatment for Grave’s disease is well recognized. However, development of Grave’s ophthalmopathy following radioiodine therapy given for toxic adenoma or toxic nodular goiter has been reported but very rarely. Hereby, we reported a case of a 69-year-old male patient who developed ophthalmopathy after receiving 30 mCi (1110 mBq) 131...

The present opinions on the therapy with L-thyroxine (L-T4) of non-toxic multinodular, as well as of non-toxic thyroid nodules are rather divergent. This treatment is based on the suppression of TSH secretion from the pitu-

There is no ideal treatment for benign multinodular goitre. Besides surgery, which is recommended for large goitres or when malignancy cannot be excluded, the non-surgical treatment options are levothyroxine therapy and radioiodine ((131)I) therapy. Conventional (131)I therapy [without recombinant human thyroid-stimulating hormone (rhTSH)] has been used for more than a decade in symptomatic non...

The objective of the study is to determine the incidence of malignancy in non toxic multinodular goiter patients who underwent thyroid surgery in our institution. This is a prospective study carried out in the Department of general surgery, Liaquat University of Medical & Health Sciences Hospital Jamshoro, from January 2011 to December 2011. A total no. of 95 cases with clinical diagnosis as no...

In hyperthyroidism three major treatment modalities are currently available: antithyroid drugs, radioiodine and surgery, each of which presents advantages and restrictions (Surk et al.,1990). RAIT is considered as the most comfortable and economical approach of hyperthyroidism treatment caused by Graves ́ disease or toxic nodular goiter. Such treatment is indicated in patients with/or without fu...

177 INTRODUCTION Thyroid surgery is one of the most commonly performed surgeries nowadays. Total thyroidectomy was only popular for indications other than cancer at the last quarter of twentieth century for fear of its complications. In this era however this operation has been the treatment of choice even for benign thyroid pathology such as multinodular goiter, toxic goiter and refractory Grav...

UNLABELLED Radioactive iodine uptake (RAIU) is a test used to differentiate hyperthyroidism from thyroiditis and to calculate the radioiodine dose for treatment of Graves' disease. We aimed to evaluate the predictive role of 24h RAIU with respect to the outcome of radioiodine therapy in patients with diffuse toxic goiter (DTG). METHODS Case records of patients with DTG treated with radioactiv...

The relationship between thyroid auto-immunity and the presence of lymphocytes in the thyroid gland has been analysed in patients with Graves' disease, toxic adenoma, and non-toxic nodular goitre. In all these conditions circulating antibody to thyroglobulin was significantly associated with lymphocytic infiltration. No similar correlation was established in the case of the complement-fixing an...

Graves' disease (GD) may be observed as an infrequent adverse effect after radioiodine therapy (RAIT) for toxic thyroid adenoma (TA) and toxic multi nodular goiter (MNG). We present a case of a 55-year-old male with a toxic nodule who was treated with RAI. After therapy, the patient's serum free triiodothyronine (fT3) and free thyroxine (fT4) levels gradually increased. Antithyroid peroxidase (...

In 1932 Hamilton and Schwartz (1) described a method for the detection of small amounts of parathyroid hormone, three to five units, in preparations of the hormone and in blood. In 1936 Hamilton and Highman (2) presented certain modifications of this test designed to make the method particularly applicable to the detection of abnormally large amounts of parathyroid hormone in the blood of patie...