Two previously healthy men who presented with hypotension, constitutional symptoms, and targetoid and discrete spotty erythematous plaques were diagnosed with toxic shock syndrome based on histopathological findings. Specifically, their biopsies revealed necrotic keratinocytes, neutrophils in the epidermis, and neutrophils surrounding dilated superficial vessels. In one case, the diagnosis of t...

OBJECTIVE Toxic shock syndrome is a rare but life-threatening complication after plastic surgery procedures. METHODS We experienced 2 cases of toxic shock syndrome after expander-based breast reconstruction caused by methicillin-resistant Staphylococcus aureus. RESULTS The first patient took a severe clinical course due to the delayed diagnosis and treatment, and the second patient recovere...

The authors report a case of a 35-year-old man with no known underlying disease who presented with fever, cellulitis with hemorrhagic blebs on the left leg, monoarthricular left knee arthritis, multiple organ failure and septic shock. His clinical syndrome was compatible with toxic shock syndrome and his blood grew alpha hemolytic (viridians) Streptococcus mitis. To our knowledge, there are few...

Toxic shock syndrome toxin 1 (TSST1)t is a 22-kD exotoxin produced by most strains ofStaphylococcus aureus isolated from patients with toxic shock syndrome (TSS) (1) . TSST1 is a potent activator of monocytes and T cells . It acts on monocytes to induce the synthesis of IL-1 and TNF (2-4) . TSSTl also triggers T cell activation and proliferation (5), as well as the production of large amounts o...