the toxicity of 7 herbicides to the three cyanobacteria was tested in this work. the results indicated that: (1) there was a highly significant relationship between dried weight or chlorophyll-a and od680nm for tested cyanobacteria; (2) the toxicity of the tested herbicides with the order from high to low was: photosynthesis-inhibiting > accase inhibitor > protox inhibiting herbicides; (3) the ...

objectives: nigella sativa (n. sativa) is an amazing herb which is used in traditional medicine for a wide range of illnesses including bronchial asthma, dysentery, gastrointestinal problems, as well as beneficial effect on blood lipids, lowering blood pressure, serum cholesterol, and triglycerides level. this study aimed to determine the toxic effect of n. sativa powder on the kidney function ...

objective: in this study we investigated the effects of spearmint (mentha spicata labiatae) on the reproductive system, fertility and number of offspring in adult male rats. materials and methods: adult wistar male rats in one control (c) and three experimental groups (i, ii and iii) received 0, 10, 20 and 40 mg/kg spearmint extract orally for 45 days, respectively.  following this treatment, t...

silicon is the element very similar to carbon, and bioactive siliconized compounds have therefore received much attention. siliconization of a compound enhances its biological activities. in the present study the hypolipidemic effect and toxicity of clofibrate and its siliconized analog, silafibrate, were compared. the experiments were performed in hypercholesterolemicwistar rats. animals recei...

diphenhydramine, as an antihistamine drug is widely used for the treatment of allergies. however, being classified as an over the counter medication and the general belief on the low adverse effect profile of this drug has made it widely accessible to the families. recent reports of diphenhydramine intoxication and mortality, noticeably in children and infants have raised some serious concerns....

purpose: to describe the clinical signs, diagnosis and treatment of toxic keratopathy in a patient who abused tetracaine drops. case report: a 32-year-old man was referred to the emergency ward of our center with persistent corneal epithelial defect associated with a ring infiltrate in the corneal stroma, without any history of ocular trauma or contact lens use. the patient was hospitalized and...

purpose : to determine the maximum non-toxic dose of recombinant human erythropoietin (epo) in rabbit eyes methods : eight rabbits (sixteen eyes) were scheduled for evaluating side effects of four intravitreal doses of 1000, 2000, 4000 and 5000 iu of epo, two rabbits for each dose. for each dose (two rabbits), the drug was injected for the right eyes. balanced salt solution (bss) was injected i...

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background pomegranate (punica granatum) is a significant source of bioactive compounds. however, its toxicity is not intensively studied. objectives the current study investigated the safety and tolerability of pomegranate peel extract (ppe) in balb/c mice. conclusions the current study showed that ppe had no toxicity and its use is suggested with potential applications against diseases. resul...

objectives colloidal drug delivery system, solid lipid nanoparticles (slns), helps to increase the solubility of the drug and its oral bioavailability. methods tamoxifen (tam) as a nonsteroidalantiestrogen drug was formulated in sln and an in vitro study was conducted to determine the cytotoxicity effect of tam-loaded slns on human breast cancer cell lines mcf-7 (estrogen receptor-positive) and...