Long Range Dependent LRD network tra c does not behave like the tra c generated by the Poisson model or other Markovian models The main di er ence is that LRD tra c increases queueing delays due to the burstiness of the tra c over many time scales LRD tra c has been measured in di erent types and sizes of networks for di erent applications eg WWW and di erent tra c aggregations Since LRD behavi...

The tra-2 gene of the nematode Caenorhabditis elegans encodes a predicted membrane protein, TRA-2A, that promotes XX hermaphrodite development. Genetic analysis suggests that tra-2 is a negative regulator of three genes that are required for male development: fem-1, fem-2, and fem-3. We report that the carboxy-terminal region of TRA-2A interacts specifically with FEM-3 in the yeast two-hybrid s...

The expression of the epitopes recognized by the monoclonal antibodies Tra-1-60 and Tra-1-81 is routinely used to assess the pluripotency status of human embryonic stem cells (hESCs) and induced pluripotent stem (iPS) cells. Although it is known that the epitopes recognized by Tra-1-60 and Tra-1-81 are carbohydrates, the exact molecular identity of these epitopes has been unclear. Glycan array ...

Background: The transverse abdominis (TrA) muscle is one of the most important muscles that contribute to the stability of the lumbar spine. Strengthening of trunk muscles that have a significant role in trunk stability is very important in the field of professional sport, sport medicine and rehabilitation of patient with low back pain (LBP). Identifying the exercises that can improve the stren...

All-trans retinoic acid (tRA) and arsenic trioxide (As(2)O(3)) induce non-cross-resistant complete clinical remission in patients with acute promyelocytic leukemia with t(15;17) translocation and target PML-RARalpha, the leukemogenic protein, by different pathways suggesting a possible therapeutic synergism. To evaluate this possibility, this study examined the effect of As(2)O(3) on tRA-induce...

ÐIn this paper, the Dynamic Trac Routing problem is de®ned as the real-time point diversion of trac during non-recurrent congestion. This dynamic trac routing problem is then formulated as a feedback control problem that determines the time-dependent split parameters at the diversion point for routing the incoming trac ̄ow onto the alternate routes in order to achieve a user-equilibrium tra...

Ten mutations are described that transform genotypic hermaphrodites of the nematode Caenorhabditis elegans into phenotypic males. These fall into three autosomal complementation groups, termed tra-1, tra-2, and tra-3. Two alleles of tra-1 produce almost complete transformation, to a fertile male phenotype; such transformed animals are useful for analyzing sex-linked genes. All alleles of tra-1 ...

Title of Document: ISOLATION AND CHARACTERIZATION OF CAENORHABDITIS BRIGGSAE TRA MUTANTS. Danielle Fay Kelleher, Master of Science, 2005 Directed By: Professor Eric S. Haag Department of Biology In order to aid in the reconstruction of the Caenorhabditis briggsae sex determination pathway, for the purposes of studying the convergent evolution of hermaphroditism and mating system change in nemat...

The Caenorhabditis elegans sex-determination gene, tra-2, is translationally regulated by two 28 nt elements (DREs) located in the 3'UTR that bind a factor called DRF. This regulation requires the laf-1 gene activity. We demonstrate that the nematode Caenorhabditis briggsae tra-2 gene and the human oncogene GLI are translationally regulated by elements that are functionally equivalent to DREs. ...