نتایج جستجو برای: transdermal patches

تعداد نتایج: 28443  

2014
Osama AA Ahmed Tarek A Ahmed Ashraf B Abdel-Naim Alaa Khedr Zainy M Banjar Mohsen I Afouna

Purpose: To utilize hydroxybutyl-β-cyclodextrin (HB-β-CD) and polyvinyl pyrrolidone (PVP) for the enhancement of the transdermal delivery of glimepiride (GMD). Methods: Matrix-type transdermal patches containing GMD, drug coprecipitate or its inclusion complex were prepared using different gelling agents, viz, hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), carbopol and chi...

Journal: :Acta pharmaceutica 2004
Amir Mehdizadeh Tayebe Toliate Mohammad Reza Rouini Sharyar Abashzadeh Farid Dorkoosh

The present research was designed to evaluate different matrix, drug-in-adhesive and reservoir formulations of fentanyl transdermal patches. The target was to design drug-in-adhesive patches (DIAPs); a full factorial design was used. Different types and amounts of liquid, pressure-sensitive adhesives (PSAs) were used and evaluated with respect to drug release and adhesive properties. A very sim...

2012
Sharad Pawar P. D. Chaudhari Jalpa K Patel

Drug delivery system relates to the production of a drug, its delivery medium, and the way of administration. Drug delivery systems are even used for administering nitroglycerin. Transdermal drug delivery system is the system in which the delivery of the active ingredients of the drug occurs by the means of skin. Various types of transdermal patches are used. There are various methods to enhanc...

Madusudhan Rao Yamsani, Pavani Sriram, Yamsani Shravan Kumar

The aim of the present study was to develop and investigate the feasibility of delivering Nebivolol as a transdermal patch by iontophoresis. The passive and electrically assisted transdermal delivery of Nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. Because of its extensive hepatic metabolism and low dos...

2013
Rakesh Kumar Sharma Navneet Sharma Sudha Rana Hosakote G. Shivkumar

Worldwide prevalence of type 2 diabetes is increasing with alarming proportions. Metformin is the first-line oral antidiabetic drug of choice for the treatment of type 2 diabetes. The objectives of the present study were to develop Metformin solid lipid nanoparticles (M-SLN) and incorporate it in the transdermal patches. M-SLN was evaluated for Particle size, Zeta potential, Surface morphology ...

Journal: :iranian journal of pharmaceutical sciences 0
jitendra banweer department of pharmacy, barkatullah university, nh-12 bhopal-462026 a. k. pathaka department of pharmacy, barkatullah university, nh-12bhopal-462026. subhash pandey glenmark pharmaceuticals ltd. andheri (e), mumbai-400026.

lisinopril dihydrate (angiotensin converting enzyme inhibitor) is a lysine derivative of enalaprilat and does not require hydrolysis to exert pharmacological activity. it has an extensive hepatic first pass metabolism resulting in a bioavailabil-ity of 6-60%. to overcome the poor bioavailability of the drug, transdermal patches have been prepared. the present study also aims at optimization of ...

Journal: :Indo Global Journal of Pharmaceutical Sciences 2014

Journal: :Journal of Scientific and Industrial Metrology 2017

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