The pathophysiological mechanisms underlying the development of spasticity are not clear, but the excitability of the disynaptic reciprocal inhibitory pathway is affected in many patients with spasticity of different origin. Patients with genetically identified autosomal dominant pure spastic paraparesis (ADPSP) develop spasticity and paresis in the legs, but usually have no symptoms in the arm...

Moving averages are one of the most popular and easy-to-use tools available to a technical analyst, and they also form the building blocks for many other technical indicators and overlays. Building a moving average (MA) model needs determining four factors of (1) approach of issuing signals, (2) technique of calculating MA, (3) length of MA, and (4) band. After a literature re...

Prokaryotic MazF family toxins cooccur with cognate antitoxins having divergent DNA-binding folds and can be of chromosomal or plasmid origin. Sequence similarity search was carried out to identify the Toxin-Antitoxin (TA) operons of MazF family followed by sequence analysis and phylogenetic studies. The genomic DNA upstream of the TA operons was searched for the presence of regulatory motifs. ...

Recovery of lower-limb function after spinal cord injury (SCI) likely depends on transmission in the corticospinal pathway. Here, we examined whether paired corticospinal-motoneuronal stimulation (PCMS) changes transmission at spinal synapses of lower-limb motoneurons in humans with chronic incomplete SCI and aged-matched controls. We used 200 pairs of stimuli where corticospinal volleys evoked...

BACKGROUND Takayasu arteritis (TA) is a rare form of chronic inflammatory granulomatous arteritis of the aorta and its major branches. Late gadolinium enhancement (LGE) with magnetic resonance imaging (MRI) has demonstrated its value for the detection of vessel wall alterations in TA. The aim of this study was to assess LGE of the coronary artery wall in patients with TA compared to patients wi...

In order to improve the corrosion and wear resistance of biomedical Ti-6Al-4V implants, a Ta₂N nanoceramic coating was synthesized on a Ti-6Al-4V substrate by the double glow discharge plasma process. The Ta₂N coating, composed of fine nanocrystals, with an average grain size of 12.8 nm, improved the surface hardness of Ti-6Al-4V and showed good contact damage tolerance and good adhesion streng...

We let Ta and Ma denote respectively the values of the time-to-event outcome and mediator that would have been observed had the exposure A been set to level a. We let Tam denote the value of the time-to-event outcome that would have been observed had the exposure, A, and mediator, M , been set to levels a and m, respectively. The average controlled direct effect comparing exposure level a to a∗...

Abstract Multi‐walled carbon nanotubes (MWCNT) were first non‐covalently functioned by tannic acid (TA), then blended with nitrile rubber (NBR) and ethylene propylene diene monomer (EPDM) NBR:EPDM:TA‐MWCNT = 70:30:5. TA‐MWCNT the composites had been characterized various techniques, including Fourier transform infrared spectroscopy (FT‐IR), Raman analysis, transmission electron microscopy (TEM)...