Flood risk assessment and mapping is required for management mitigation of flood in mountain cities. However, the specific characteristics population, society, economy, environment, transportation other disaster-bearing bodies various regions cities are significantly different, which increases uncertainty index weight accuracy. To overcome these problems, triangular fuzzy number-based analytica...

Software quality requirements are essential part for the success of software development. Defined and guaranteed quality in software development requires identifying, refining, and predicting quality properties by appropriate means. Goal models of goal oriented requirements engineering (GORE) and quality models are useful for modelling of functional goals as well as for quality goals. Once the ...

We previously reported that Rab1a is associated with asialoorosomucoid (ASOR)-containing early endocytic vesicles, where it is required for their microtubule-based motility. In Rab1a knockdown (KD) cell lines, ASOR failed to segregate from its receptor and, consequently, did not reach lysosomes for degradation, indicating a defect in early endosome sorting. Although Rab1 is required for Golgi/e...

OBJECTIVE To compare the fixation stability in the femoral head with sliding hip screw versus helical blade designs for unstable, intertrochanteric hip fractures. METHODS A simulated, unstable intertrochanteric hip fracture was created in six pairs of cadaveric femurs. One of each pair was treated using an intramedullary nail with a sliding hip screw (ITST) for femoral head fixation and the o...

.....................................................................................................42 Introduction ................................................................................................42 Materials and Methods................................................................................44 Cell culture and transfections .................................................

Preferred sites of endocytosis have been observed in various cell types, but whether they occur randomly or are linked to cellular cues is debated. Here, we quantified the sites of endocytosis of transferrin (Tfn) and epidermal growth factor (EGF) in cells whose adhesion geometry was defined by micropatterns. 3D probabilistic density maps revealed that Tfn was enriched in adhesive sites during ...

Dynamin is the mammalian homologue to the Drosophila shibire gene product. Mutations in this 100-kD GTPase cause a pleiotropic defect in endocytosis. To further investigate its role, we generated stable HeLa cell lines expressing either wild-type dynamin or a mutant defective in GTP binding and hydrolysis driven by a tightly controlled, tetracycline-inducible promoter. Overexpression of wild-ty...

One important topic that raised concern among researchers and population is the threat posed by widespread presence of single-use plastic items, which has become a part day-to-day life. An urgent need to build plan manufacturers/ investors give due over environmental preservation. A number challenges are yet be addressed for implementation sustainable manufacturing concerned with environment; t...

Although the susceptibility of dermatophytes to antifungal drugs is well documented in humans, the effectiveness in animals has not been previously investigated. The in vitro susceptibility of 54 clinical isolates from animal dermatophytoses to ketoconazole (KTZ), itaconazole (ITZ) and terbinafine (TFN) was measured using microdilution assay (CLSI M38-A2 test) and by the E-test (KTZ and ITZ). A...

One of the limiting factors in good performance of forward osmosis (FO) membranes is the internal concentration polarization (ICP). To reduce ICP, thin film nanocomposite forward osmosis (TFN-FO) membranes were fabricated by adding different amounts of graphene oxide (GO) nanoplates (0-1 wt. %) to polymer matrix of polysulfone (PSf) substrate. The prepared nanocomposite membranes exhibited both...