In previous studies, the neuroprotective effect of progestrone in diffuse traumatic brain injury has been shown. This study used mifepristone (RU-486), a potent progesterone receptor antagonist, to evaluatethe hypothesis that the neuroprotective effect of progesterone in traumatic brain injury is mediated by the progesterone receptors. The ovariectomized rats were divided into 6 groups. Brain i...

syringobulbiais very rare condition defined as slit-like fluid cavity in the brain stem. several conditions have been reported to be associated with syringobulbia including neoplasms, spinal cord traumas or lesions such as tethered cord, hind-brain herniation, infections such as meningitis and in isolation.although post-traumatic syringomyelia has been wieldy described previously, traumatic bra...

traumatic brain injury (tbi) is one of the most common neurological diseases with no definite treatment. erythropoietin (epo) and progesterone (prog) have been shown to have neuroprotective effects in different types of experimental brain injury models. this study was designed to determine the effect of epo, prog and combination of epo/prog on neurological outcome after traumatic brain injury. ...

background & aim: using pharmaceutical agents in treatment of aphasia has caught the attention of many neurologists and neuroscientists. this short review study has sought the role of pharmacotherapy in treatment of aphasia, a linguistic impairment after acquired brain lesions. the pharmacological principles and mechanisms related to the effects of drugs used in aphasia rehabilitation are point...

conclusion tf-cbt for patients with acute stress disorder has been shown to be efficacious in reducing the likelihood of subsequent development of ptsd. despite the impressive level of empirical support for tf-cbt, many professionals remain unaware of its advantages and many children and parents who could benefit do not receive such treatment. further more, in iran, there may not yet be any tf-...

purpose: to compare the effect of high dose intravenous corticosteroid therapy with placebo in the treatment of recent traumatic optic neuropathy (ton). methods: in a double masked-placebo controlled clinical trial, 31 eyes of 31 patients were randomly assigned into two groups. only patients with history of ophthalmic or head trauma within the past 7 days were included. unconscious patients, th...

conclusions an extremely rare condition, a spontaneous intracranial pneumocephalus with skull base defect origin could be considered as a possible diagnosis in patients with sudden and severe headache. we can safely conclude that medical treatment and close follow-up is an effective mode of therapy in this patient. introduction spontaneous pneumocephalus without any pathological condition is ve...

abstract objective: to determine the effects of glycemic level on outcome patients with traumatic brain injury . m e t h od s :   from september 2010 to december 2012, all medical records of adult patients with tbi admitted to the emergency room of laura daniela clinic in valledupar city, colombia, south america were enrolled. both genders between 18 and 85 years who referred during the first 4...