Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common pharmaceuticals used worldwide. They widely detected in natural waters due to their persistence wastewater treatment, and removal is desirable management. As a contribution tackle this challenge, study explores magnetic quaternary chitosan-based nanosorbents for effective magnetically assisted of three NSAIDs (diclofenac, ...

A series of water-soluble cationic chitosan derivatives were prepared by chemoselective functionalization at the amino group of five different parent chitosans having varying degrees of acetylation and molecular weight. The quaternary moieties were introduced at different alkyl spacer lengths from the polymer backbone (C-0, C-2 and C-6) with the aid of 3,6-di-O-tert-butyldimethylsilyl protectio...

BACKGROUND The production of protein drugs has recently increased due to advances in biotechnology, but their clinical use is generally limited to parenteral administration due to low absorption in non-parenteral administration. Therefore, non-parenteral delivery systems allowing sufficient absorption draw much attention. METHODS Microparticles (MP) were prepared using chitosan-4-thio-butylam...

A tube type mini electrode has been made to detect paracetamol levels in herbal medicine, the is of a glass with diameter 0.7 cm, length 3 cm. As membrane mixture chitosan, activated carbon from rice husk, and cetyl trimethyl ammonium (CTA)-paracetamol. The internal solution standard 0.01 M phosphoric acid pH 2. average sensitivity sensor (22.60 ± 0.01) mV/decade linear concentration range 10-6...

OBJECTIVE To obtain information on practitioner experience in the use of the Genesys HydroThermAblator (HTA) System under normal clinical conditions through documentation of the system's acute safety features, in terms of burn rates, and its technical reliability. STUDY DESIGN This was a prospective, observational, multicenter, postmarket interventional clinical trial with outcome measures of...

We recently reported that electret, which was prepared by a corona charging system with polypropylene film, could enhance the transdermal delivery of several drugs of low molecular weight. The aim of this study was to investigate whether electret could enhance the transdermal delivery of protein drugs by N-trimethyl chitosan nanoparticles (TMC NPs) prepared by an ionic gelation method. A series...

OBJECTIVE To assess the clinical relevance and newsworthiness of the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme funded reports. STUDY DESIGN Retrospective cohort study. SETTING The cohort included 311 NIHR HTA Programme funded reports publishing in HTA in the period 1 January 2007-31 December 2012. The McMaster Online Rating of Evidence (MO...