This study shows that human bile, at a concentration in the range of that found in the intestinal lumen, inhibited the hydrolysis of emulsified triolein by pancreatic lipase in vitro. The addition of colipase in excess to lipase failed to restore lipolytic activity. In contrast, a partially degraded emulsion of triolein containing diacylglycerol, monoacylglycerol and free fatty acid was hydroly...

Pulmonary fat embolism occurs frequently after trauma but its functional significance is often unclear. To obtain direct evidence of lung damage caused by fat embolism we have measured changes in permeability of the alveolar-capillary interface. A permeability index was derived from the half time clearance from lung to blood (T1/2LB) of 99mTcDTPA introduced into the lung in a 1 ml bolus. Three ...

The effect of a diet containing triglycerides of different fatty acid composition on hepatic 7alpha-hydroxylation of cholesterol was studied. 7alpha-Hydroxylation of exogenous as well as endogenous cholesterol was significantly lower in the liver of rats fed trilinolein and triolein than in those fed tripalmitin and trierucin. The concentration of cytochrome P-450 in liver microsomes was signif...

PURPOSE The purpose of this study was to evaluate the cerebral hemodynamic change in the hyperacute stage of cerebral fat embolism induced by triolein emulsion, by using MR perfusion imaging in cat brains. METHODS By using the femoral arterial approach, the internal carotid arteries of 14 cats were infused with an emulsion of triolein 0.05 mL. T2-weighted (T2WI), diffusion-weighted (DWI), app...

BACKGROUND AND PURPOSE In fat embolism, free fatty acid is more toxic than neutral fat in terms of tissue damage. We evaluated the hyperacute embolic effects of triolein and oleic acid in cat brains by using MR imaging and electron microscopy. METHODS T2-weighted imaging, diffusion-weighted imaging, and contrast-enhanced T1-weighted imaging were performed in cat brains after the injection of ...

Ultrasonic spraying was used in a three-phase reactor to produce small droplets of triolein mixed with CaO as solid catalyst at temperatures above the boiling point methanol for enhancement transesterification triolein. Droplets fell countercurrent flow and were collected bottom reactor, followed by circulation ultrasonic spray system. The experimental parameters included rates 2.5–9.0 mL/min, ...

OBJECTIVE The purpose of this study is to evaluate the effect of dexamethasone on the damaged blood-ocular barrier caused by triolein emulsion, using contrast-enhanced MR imaging. MATERIALS AND METHODS An emulsion of 0.1-mL triolein in 20 mL of saline was infused into the carotid arteries of 32 cats, 12 cats were placed in the treatment group and 18 cats were placed in the Control group. Thir...