نتایج جستجو برای: triple negative

تعداد نتایج: 572352  

Journal: :Molecular cancer therapeutics 2011
Tongrui Liu Rami Yacoub LaTonia D Taliaferro-Smith Shi-Yong Sun Tisheeka R Graham Ryan Dolan Christine Lobo Mourad Tighiouart Lily Yang Amy Adams Ruth M O'Regan

Triple-negative breast cancers, which lack estrogen receptor, progesterone receptor, and HER2/neu overexpression, account for approximately 15% of breast cancers, but occur more commonly in African Americans. The poor survival outcomes seen with triple-negative breast cancers patients are, in part, due to a lack of therapeutic targets. Epidermal growth factor receptor (EGFR) is overexpressed in...

2012
Wen-Hung Kuo Yao-Yin Chang Liang-Chuan Lai Mong-Hsun Tsai Chuhsing Kate Hsiao King-Jen Chang Eric Y. Chuang

BACKGROUND Triple-negative breast cancer is a subtype of breast cancer with aggressive tumor behavior and distinct disease etiology. Due to the lack of an effective targeted medicine, treatment options for triple-negative breast cancer are few and recurrence rates are high. Although various multi-gene prognostic markers have been proposed for the prediction of breast cancer outcome, most of the...

Journal: :The American Journal of Pathology 2018

Journal: :Expert Opinion on Pharmacotherapy 2015

Journal: :International Journal of Molecular Sciences 2013

2012
Chidambharam Choccalingam Lakshmi Rao Sruti Rao

UNLABELLED Aims of the study were to evaluate the expression Cytokeratin 5/6(CK5/6) and Epidermal Growth Factor Receptor (EGFR) among triple negative breast cancers and high grade infiltrating duct carcinomas. Further to probe if triple negative phenotype can be a surrogate marker for basal phenotype and to correlate the expression of basal markers with disease free survivals among triple negat...

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