BACKGROUND AND AIM Metronidazole and tetracycline-based second-line quadruple therapy, widely used for Helicobacter pylori infection, often ends up in failure due to antibiotic resistance and poor compliance in Korea. Our aim is to evaluate the efficacy and tolerability of moxifloxacin-based triple therapy as an alternative second-line treatment for H. pylori infection. METHODS The subjects c...

Approximately half of the world’s population is infected by Helicobacter pylori [1], which causes various gastrointestinal diseases including gastritis, peptic ulcer, gastric mucosaassociated lymphoid tissue lymphoma, and gastric cancer [2,3]. Korean guidelines, which were revised in 2013, by the Korean College of Helicobacter and Upper Gastrointestinal Research strongly recommend that H. pylor...

BACKGROUND After an acute coronary syndrome, dual antiplatelet therapy with clopidogrel plus aspirin is still a standard of care, but several new approaches have been investigated. OBJECTIVES The present study re-examined the studies published thus far on this topic to evaluate the effectiveness of dual antiplatelet therapy in comparison to some of these new approaches (mainly, ticagrelor + a...

aim : the aim of this study was to compare the half-dose and full-dose triple therapy regimens for helicobacter pylori ( hp ) eradication in patients with end-stage renal disease. background : h. pylori is one the most important causes of dyspepsia in patients with end-stage renal disease (esrd). patients and methods : sixty-six patients with esrd were enrolled in the study with hp infection an...

background and purpose: successful treatment of helicobacter pylori infection causes not only eradication of pathogen, but also prevents the associated diseases such as peptic ulcer, gastric carcinoma and lymphoma. the aim of this study was to evaluate the efficacy of 7 days triple therapy as a lowest drug resistance, shortest duration and fewer numbers of drugs in children. materials and metho...

Correspondence to: Battal Altun Department of Internal Medicine, Kasımpasa Military Hospital, Yesilkoy, Istanbul 34149, Turkey Tel: +90-5415429657, E-mail: [email protected] Received on November 30, 2014. Revised on January 6, 2015. Accepted on January 7, 2015. Published online June 19, 2015 pISSN 1976-2283 eISSN 2005-1212 http://dx.doi.org/10.5009/gnl14469 To the Editor: We read the articl...

conclusions our results indicated a reversible increase in rbv bioavailability after telaprevir exposure, which might be linked to the impairment of the gfr. this also suggests a rbv-telaprevir pharmacological interaction, a possible source of severe anemia observed under triple therapy. these results suggest that rbv pharmacological monitoring may be clinically relevant, especially in the cont...

BACKGROUND Standard triple therapy for Helicobacter pylori infection fails in up to one quarter of patients. Levofloxacin-based triple therapy may be more efficacious. OBJECTIVE The aim of this paper was to compare levofloxacin and proton pump inhibitor-based triple therapy with standard triple therapy for H. pylori infection. METHODS PubMed, Embase, Cochrane Central Register of Controlled ...

BACKGROUND The success rates of therapies for treating Helicobacter pylori vary greatly worldwide and the ideal treatment has yet to be clearly established. AIMS A systematic review was carried out to evaluate the effectiveness of current first and second-line therapies in treating H.pylori infection. METHODS Two researchers independently carried out Internet search engine reviews (PUBMED, ...