background: myocardial infarction is the major cause of morbidity and mortality in industrialized countries. platelet count and the mean platelet volume (mpv), a simple and reliable indicator of platelet size which correlates with platelet activation, might associate with troponin in acute chest pain. methods: we analyzed mpv of 851 patients who were admitted to rasoul-e-akram hospital with acu...

BACKGROUND Elevations of cardiac enzymes are commonly used to indicate myocardial ischemia, but they can be elevated due to other conditions. Different forms of Troponin (cTnT, sTnT, cTnI), can cause cross-reactivity in the Troponin T assay, leading to false positives. This report describes a patient with polymyositis who had elevated Troponin T, but no cardiac abnormalities. The purpose is to ...

BACKGROUND Perinatal asphyxia is associated with cardiac dysfunction. This may be secondary to myocardial ischaemia. Cardiac troponin T is the ideal marker for myocardial necrosis. Elevated levels in cord blood may be associated with intrauterine hypoxia and increased perinatal morbidity. AIMS To establish an upper limit of normal for cardiac troponin T concentration in the cord blood of infa...

myocardial infarction (mi) is one of the most important health burdens worldwide. aspirin as an non- steroid anti—inflammatory drug, has been proven to be a protective factor to decrease the incidence, however its effect of mi size is still unknown. we designed this study to compare the biomarkers after mi in patients with and without aspirin intake. 378 patients were enrolled and the results s...

predictors of adverse cardiac events in more than 600 patients with the acute coronary syndrome. Using receiver-operator curves and a multiple regression model, they concluded that troponin T had a greater sensitivity than troponin I in detecting patients who would eventually have a myocardial infarction and/or die within 30 days. Furthermore, the concern that tropo¬ nin T is inappropriately el...

BACKGROUND Cardiac troponin concentrations are used to identify patients who would benefit from urgent revascularization for acute coronary syndromes. We hypothesized that they might be used in patients with stable ischemic heart disease to identify those at high risk for cardiovascular events who might also benefit from prompt coronary revascularization. METHODS We measured the cardiac tropo...

BACKGROUND Myocardial infarction (MI) is diagnosed by the finding of a single cardiac troponin value above the 99th percentile and a significant time-dependent change in cardiac troponin concentration. The aim of this study was to determine the 90-min and weekly biological variations, the reference change value (RCV), and the index of individuality (II) of high-sensitivity cardiac troponin T (h...

The development of highly sensitive assays for cardiac troponin T (hs-cTnT) and cardiac troponin I (hscTnI) represents the latest technological advance in a field that has witnessed continual progression toward more sensitive and more precise tools for detecting cardiac injury. The hs-cTnT assay, for example, can detect cTnT concentrations 10-fold lower than the current fourth-generation assay,...

BACKGROUND Requests for troponin T, a biomarker for myocardial infarction, may be sent in a variety of clinical situations. In most cases, a single sample 12 hours or more after symptom onset should be sufficient for diagnosis. We chose to investigate how troponin T testing is used in our hospital with emphasis on those who had serial rather than single troponin measurements during their hospit...