Plasmids that contain Saccharomyces cerevisiae TG1-3 telomere repeat sequences (TRS plasmids) segregate efficiently during mitosis. Mutations in histone H4 reduce the efficiency of TRS-mediated plasmid segregation, suggesting that chromatin structure is involved in this process. Sir2, Sir3 and Sir4 are required for the transcriptional repression of genes located at the silent mating type loci (...

INTRODUCTION This study aimed at identifying the factors that influence the incidence of temporomandibular disorders (TMD)-related symptoms (TRS) in a Japanese working population. METHODS Our study subjects comprised of 1,969 employees from the same Japanese company. The subjects were assessed using a questionnaire that covered both TRS and the work environment. TRS were measured from 4 items...

Right-linear finite path overlapping TRS are shown to effectively preserve recognizability. The class of right-linear finite path overlapping TRS properly includes the class of linear generalized semimonadic TRS and the class of inverse left-linear growing TRS, which are known to effectively preserve recognizability.

Treatment resistance in schizophrenia is a fairly common problem faced by psychiatrists worldwide. The concept and definition of Treatment Resistant Schizophrenia (TRS) is still far from satisfactory. Data suggests the presence of biological factors underlying TRS. Second generation antipsychotics are advocated for patients with TRS. However, till date, clozapine remains the treatment of choice...

BACKGROUND The symptoms of temporomandibular disorders (TMD) are directly influenced by numerous factors, and it is thought that additional factors exert indirect influences. However, the relationships between TMD-related symptoms (TRS) and these contributing factors are largely unknown. Thus, the goal of the present study was to investigate influences on TRS in a working population by determin...

We study the trust region subproblem (TRS) of minimizing a nonconvex quadratic function over the unit ball with additional conic constraints. Despite having a nonconvex objective, it is known that the TRS and a number of its variants are polynomial-time solvable. In this paper, we follow a second-order cone based approach to derive an exact convex formulation of the TRS, and under slightly stro...

We study large scale extended trust region subproblems (eTRS) i.e., the minimization of a general quadratic function subject to a norm constraint, known as the trust region subproblem (TRS) but with an additional linear inequality constraint. It is well known that strong duality holds for the TRS and that there are efficient algorithms for solving large scale TRS problems. It is also known that...

Computation with a term rewrite system (TRS) consists in the application of its rules from a given starting term until a normal form is reached, which is considered the result of the computation. The unique normalization (UN) property for a TRS R states that any starting term can reach at most one normal form when R is used, i.e. that the computation with R is unique. We study the decidability ...