We found that resveratrol enhances interferon (IFN)-γ-induced tryptophanyl-tRNA-synthetase (TTS) expression in bone marrow- derived dendritic cells (BMDCs). Resveratrol-induced TTS expression is associated with glycogen synthase kinase-3β (GSK-3β) activity. In addition, we found that resveratrol regulates naïve CD8+ T-cell polarization by modulating GSK-3β activity in IFN-γ-stimulated BMDCs, an...

Speech synthesis or text-to-speech (TTS) systems are currently available for a number of the world’s major languages, but for thousands of other, unsupported, languages no such technology is available. While awaiting the development of such technology, we propose using an existing TTS system for a major language (the base language, BL) to “fake” TTS for an unsupported language (the target langu...

Individuals with vision loss use text-to-speech (TTS) for most of their interaction with devices, and rely on the quality of synthetic voices to a much larger extent than any other user group. A significant amount of local synthesis requests for Google TTS comes from TalkBack, the Android screenreader, making it our top client and making the visually-impaired users the heaviest consumers of the...

Part-of-speech tagging is needed for French Text-to-Speech (TTS) synthesis to disambiguate the pronunciation of homograph heterophones, liaison instances, and eventually to model intonational contours. A core problem in the part-of-speech tagging in French TTS is to decide on the tagset used for the tagger and the tagset needed by TTS. We carried out a number of experiments on several sizes of ...

S ince its initial description , Takotsubo cardiomyopathy has generated much debate and interest. Over the past 25 years, much progress has been made in understanding this syndrome. While the clinical presentation and characteristics have been well described and agreed upon, the etiology is a bit more of a debate. At present, the most commonly accepted theory on the pathophysiology of Takotsubo...

OBJECTIVE To determine whether biofilm formation on silicone tympanostomy tubes (TTs) is prevented by polyvinylpyrrolidone (PVP) coating. DESIGN In vitro microbiologic study. SUBJECTS Silicone TTs with and without a PVP coating. INTERVENTION The TTs were exposed to blood or phosphate-buffered saline and cultured with Pseudomonas aeruginosa or Staphylococcus aureus. After 4 days, antibioti...

ABSTRACT: Given the increasing application of TTS synthesis in commercial and clinical settings, there is a need to develop methods of evaluation from the user’s perspective. An experiment is reported that compares the effect of two factors, voice gender and signal quality, on the intelligibility of three TTS systems from the user’s point of view. It was hypothesised that male voiced TTS would ...

Text-to-speech (TTS) systems for many widely spoken languages have been developed and evolved over the last few decades. Such systems are being used in many different fields. Since these TTS systems have differences in the perceived sound quality, many speech quality test methods have been proposed to compare and evaluate their performance. Test materials for these tests, however, are language ...