Premature ovarian failure (POF) is characterized by amenorrhea and high serum levels of follicle-stimulating hormone (FSH). POF causes female infertility and represents a substantial women's health risk affecting 1% of women by age 40. Although ovarian autoimmunity has been associated with POF, the identity of ovarian Ags recognized is unknown. In this study, we show that autoimmune-targeted di...

Subphrenic abscess though a common presentation itself encountered in surgical practice due to various cause, tubercular subphrenic the absence of coexisting tuberculous abdomen presenting as complication pulmonary tuberculosis is extremely rare. Only very few cases have been reported an extrapulmonary manifestation so far. We report case isolated sub-diaphragmatic which responded well with ant...

BACKGROUND Tuberculosis kills five lakh patients every year in India, commonest being pulmonary tuberculosis and is often associated with effusion. Delay in diagnosis and treatment results in poor prognosis. Several studies have suggested the role of adenosine deaminase (ADA) in the diagnosis of tuberculous pleural effusions, but false-positive results from lymphocytic effusions have also been ...

we carried out prospective study on 121 cases of cervical tuberculous lymphadenitis during a 5-years period (1990-1995) in order to determine the correlation between clinical, histological and microbiological finding in establishing the tuberculous lymphadenitis diagnosis. biopsy was done in 96 cases, of which 93 specimens (96%) were compatible with tuberculous lymphadenitis, with 17 cases posi...

Premature ovarian failure (POF) is a heterogeneous syndrome with several causative factors. Autoimmune mechanisms are involved in pathogenesis of 4-30 % of POF cases. The present review focuses on the role of autoimmunity in the pathophysiology of POF. The evidences for an autoimmune etiology are: demonstration of ovarian autoantibodies, the presence of lymphocytic oophoritis, and association w...

Pelvic inflammatory disease (PID) is one of the most commonly encountered serious infectious disease entities in gynecology. The past decade has witnessed many advances in our understanding of the pathogenesis of PID. It is now evident that such pelvic infections are largely polymicrobial in origin, with major involvement by anaerobic organisms. Salpingo-oophoritis is a part of the spectrum of ...