نتایج جستجو برای: tubulin gene
تعداد نتایج: 1149291 فیلتر نتایج به سال:
We have tested the functional capacity of different beta tubulin isoforms in vivo by expressing beta 3-tubulin either in place of or in addition to beta 2-tubulin in the male germ line of Drosophila melanogaster. The testes-specific isoform, beta 2, is conserved relative to major metazoan beta tubulins, while the developmentally regulated isoform, beta 3, is considerably divergent in sequence. ...
During Drosophila embryogenesis, the beta 1 tubulin gene (beta Tub56D) is expressed in the CNS and PNS as well as in the apodemes. In this report we determine the regulation of beta 1 tubulin gene expression during formation of the attachment sites of the somatic muscles, the apodemes. The process was analysed in transgenic flies carrying beta 1 enhancer-hsp70 promoter-lacZ fusion constructs. E...
We report a transient expression transfection system in Leishmania enriettii. A hybrid gene containing an intergenic region of the alpha-tubulin cluster and the bacterial chloramphenicol acetyltransferase (CAT; EC 2.3.1.28) gene is expressed after transfection of L. enriettii with the hybrid plasmid. The expression of the CAT gene is dependent on the presence of sequences from the alpha-tubulin...
Microtubule networks are important for many vital processes such as mitosis, cell polarity, and differentiation. Ciliary architecture and function closely depend on the microtubule cytoskeleton, and recent studies suggest a role of apical cilia of renal epithelia in the pathogenesis of polycystic kidney disease. This study evaluates the localization, potential interacting partners, and function...
We report the powdery mildew Golovinomyces ambrosiae for first time on silverleaf nightshade (Solanum azureum), a host plant endemic to northern Sinaloa and southern Sonora, Mexico. No teleomorph was observed, requiring fungal species be identified based morphological characteristics of anamorph. Phylogenetic analyses ITS region partial sequence β-tubulin gene from four specimens confirmed iden...
Cellular microtubules composed of α-β-tubulin heterodimers that are essential for cell shape, division, and intracellular transport are valid targets for anticancer therapy. However, not all the conserved but differentially expressed members of the β-tubulin gene superfamily have been investigated for their role in these settings. In this study, we examined roles for the hematologic isoform β-t...
Species of Pestalotiopsis were mainly introduced as endophytes, plant pathogens or saprobes from various hosts. In this study, ten strains isolated Ficus macrocarpa, Phoebe zhennan and Spatholobus suberectus in China. Based on multilocus phylogenies the internal transcribed spacer (ITS), partial translation elongation factor 1-alpha gene (tef1α) beta-tubulin (tub2), conjunction with morphologic...
Plagiodera versicolora (Coleoptera: Chrysomelidae) is one of the most destructive pests Salicaceae worldwide, which has established complex interactions with surrounding organisms. Uncovering molecular mechanisms some antagonistic would facilitate development environmentally friendly pest insect management strategies. Suitable reference genes are essential for reliable qPCR and gene expression ...
An essential component of microtubules, α-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat α-tubulin genes has enabled...
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