There is no effective treatment for prostate cancer arising after androgen ablation. Previous studies have analyzed the short-term effects of androgen ablation on the immune system and suggest an abatement of immune suppression by hormone removal. Because castration-resistant disease can arise years after treatment, it is crucial to determine the duration of immune potentiation by castration. B...

A mathematical model of drug transport provides an ideal strategy to optimize intratumoral drug delivery implants to supplement radiofrequency (RF) ablation for tumor treatment. To simulate doxorubicin transport in non-ablated and ablated liver tumors, a one-dimensional, cylindrically symmetric transport model was generated using a finite element method (FEM). Parameters of this model, the diff...

Image-guided tumor ablation for lung malignancies has emerged as a treatment modality for medically inoperable patients. Overall, image-guided lung tumor ablation is a minimally invasive procedure that has an acceptable safety profile and less impact on lung function. This is important for patients with poor pulmonary and/or cardiac functions or with multiple comorbidities, which prevent them f...

Objective: This present study was aimed to assess the effectiveness and reliability of CT-guided nanoknife ablation in retroperitoneal tumor treatment. Methods: 2 retroperitoneal tumor patients were selected, including one pancreatic cancer patient and one colorectal cancer retroperitoneal metastatic tumor patient. The surgery was performed under general anesthesia with large aperture multi-sli...

Hormone ablation therapy typically causes regression of prostate cancer and represents an important means of treating this disease, particularly after metastasis. However, hormone therapy inevitably loses its effectiveness as tumors become androgen-independent, and this conversion often leads to death because of subsequent poor responses to other forms of treatment. Because environmental factor...

OBJECTIVES To analyze the comparison between the treatment area of 15Gage internally cooled electrodes and 17 Gage Cool Wet-tip(CWT) electrodes. They are manufactured to broaden treatment area of the tumor in the radiofrequency ablation of hepatocellular carcinoma(HCC). METHODS The study was designed for 62 patients with a mean age of 61, ranging from 44 to 87 years. The sample comprised of p...

PURPOSE To determine whether tissue visible light spectroscopy (VLS) used during radiofrequency (RF) ablation of liver tumors could aid in detecting when tissue becomes adequately ablated, locate grossly ablated regions long after temperature and hydration measures would no longer be reliable, and differentiate tumor from normal hepatic tissue based on VLS spectral characteristics. MATERIALS ...

Tumor ablation is a minimally invasive approach commonly used in the treatment of liver tumors. Over last two decades, percutaneous radiofrequency (RFA) has been widely for primary tumors and small metastases, especially liver. Effective RFA can be accomplished by complete tumor accompanied margin resection at least 0.5 cm. One methods ablation. The overall disease-free survival rate was found ...

According to a 2012 American Medical Association publication (Clinical Examples in Radiology, Vol. 8, Issue 3; Summer 2012), “microwave is part of the radiofrequency spectrum, and simply uses a different part of the radiofrequency spectrum to develop heat energy to destroy abnormal tissue.” Therefore, they instruct that microwave ablation should be reported using the CPT codes for radiofrequenc...