نتایج جستجو برای: txnrd1

تعداد نتایج: 165  

Journal: :The Journal of biological chemistry 2008
Pascal Dammeyer Anastasios E Damdimopoulos Tomas Nordman Alberto Jiménez Antonio Miranda-Vizuete Elias S J Arnér

The human thioredoxin system has a wide range of functions in cells including regulation of cell proliferation and differentiation, immune system modulation, antioxidant defense, redox control of transcription factor activity, and promotion of cancer development. A key component of this enzymatic system is the selenoprotein thioredoxin reductase 1 (TrxR1), encoded by the TXNRD1 gene. Transcript...

Journal: :Physiological genomics 2008
Jeong-In Lee John E Dominy Angelos K Sikalidis Lawrence L Hirschberger Wei Wang Martha H Stipanuk

To further define genes that are differentially expressed during cysteine deprivation and to evaluate the roles of amino acid deprivation vs. oxidative stress in the response to cysteine deprivation, we assessed gene expression in human hepatoma cells cultured in complete or cysteine-deficient medium. Overall, C3A cells responded to cysteine deprivation by activation of the eukaryotic initiatio...

2016
Atsushi Yoshino Natalia Polouliakh Akira Meguro Masaki Takeuchi Tatsukata Kawagoe Nobuhisa Mizuki

Components of fish roe possess antioxidant and antiaging activities, making them potentially very beneficial natural resources. Here, we investigated chum salmon eggs (CSEs) as a source of active ingredients, including vitamins, unsaturated fatty acids, and proteins. We incubated human dermal fibroblast cultures for 48 hours with high and low concentrations of CSE extracts and analyzed changes ...

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