OBJECTIVE The goal of this study was to evaluate the effects of perforation edge approximation and direct application of basic fibroblast growth factor (bFGF) each alone on the healing of large traumatic tympanic membrane perforations with inverted edges in humans. STUDY DESIGN Prospective, sequential allocation, three-armed, controlled clinical study. SETTING University-affiliated teaching...

Background Assisted reproductive techniques (ART) are used with increasing frequency worldwide. The present research was conducted to determine the effects of ART on hearing defects and ear abnormalities. MaterialsAndMethods n a descriptive, cross-sectional, non-randomized study, the status of hearing and ear abnormalities was assessed in 300 newborns conceived by ART at Royan Institute, Tehran...

Chronic suppurative otitis media is characterized by the presence of a persistent perforation of the tympanic membrane. Accurate estimation of the perforation size is helpful in clinical management and research. In this study, a computer program was developed to calculate the percentage of a perforation relative to the whole tympanic membrane including the pars tensa and pars flaccida. In order...

OBJECTIVE To describe a relatively unknown clinical entity - inflammatory cast of the tympanic membrane after acute otitis media - and its simple out-patient treatment. STUDY DESIGN Retrospective review of case series. SETTING Subspecialty practice at a tertiary hospital. PATIENTS Seven patients diagnosed previously with acute otitis media with perforation or otitis externa, and with pers...