Type 2 Diabetes Mellitus (T2DM) is a chronic condition characterized by high levels of blood glucose. In the United Kingdom (UK), about 7 million people are affected with Impaired Glucose Regulation (IGR) otherwise called prediabetes. T2DM is preventable in those at risk of developing the condition and early detection of T2DM can reduce diabetes related complications. Risk scores are a non-inva...

Diabetes Mellitus type 2 (T2DM) is the most common form of diabetes [WHO (2008)]. More than 29 million people in the United States are affected by T2DM and another 86 million are in a state of prediabetes, a condition that exhibits high risk to progress into diabetes [NIH (2014)]. Many T2DM cases can be prevented or avoided by improved awareness and lifestyle adjustments [NIH (2014)]. Our proje...

BACKGROUND Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high in type 1 diabetes mellitus however, there are scarce data a...

Until recently, the majority of cases of diabetes mellitus among children and adolescents were immune-mediated type 1a diabetes. Obesity has led to a dramatic increase in the incidence of type 2 diabetes (T2DM) among children and adolescents over the past 2 decades. Obesity is strongly associated with insulin resistance, which, when coupled with relative insulin deficiency, leads to the develop...

background: diabetes mellitus (dm) is a health concern which leads to complications such as retinopathy. pakistan has 6.9 million people living with dm and this toll will be doubled by 2025. objective: to determine serum il-6 and il-17 of type 2 diabetes mellitus (t2dm) patients with retinopathy. methods: in this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...

Introduction: Diabetes is chronic disease which characterised by defect in insulin secretion and action leading to hyperglycaemia. Aim: To detect protein carbonyl as oxidative stress marker Type 2 Mellitus (T2DM). Materials Methods: The present cross-sectional study was conducted on 100 subjects (aged 40 70 years) out of 50 were T2DM normal individuals. Serum tested for Fasting Blood Sugar (FBS...

Diabetic ketoacidosis (DKA) has been considered a key clinical feature of Type 1 diabetes mellitus; however, increasing evidence indicates that DKA is also a common feature of Type 2 diabetes (T2DM). Many cases of DKA develop under stressful conditions such as trauma or infection but an increasing number of cases without precipitating cause have been reported in children and adults with T2DM. S...

The Indian Diabetes Risk Score was initially developed by the Madras Diabetes Research Foundation (MDRF-IDRS) to help detect undiagnosed Type 2 diabetes (T2DM) in the community. Soon it was found that the MDRF-IDRS could also help to predict incident diabetes, metabolic syndrome, coronary artery disease (CAD), non-alcoholic fatty liver disease as well as sleep disorders in the community. It hel...