To determine whether the "congestive" gastropathy associated with portal hypertension showed distinctive histological features independent of inflammatory gastritis, endoscopic biopsy specimens of gastric mucosa from 23 patients with portal hypertension and 25 patients with non-ulcer dyspepsia were examined. Active chronic gastritis associated with Campylobacter pylori was found in three patien...

Patients with functional dyspepsia (FD) would have a greater prevalence of treatable psychiatric disorders, higher scores on measures of psychiatric symptomatology and characteristic symptoms distinguishing them from those with duodenal ulcer (DU). The aim of the work is to study the prevalence of psychiatric disorders and somatic symptoms in patients with functional dyspepsia and in comparison...

BACKGROUND Non-ulcer dyspepsia is predominantly a self-managed condition, although it accounts for a significant number of general practitioner consultations and hospital referrals. Herbal medicinal products are often used for the relief of dyspeptic symptoms. AIMS : To critically assess the evidence for and against herbal medicinal products for the treatment of non-ulcer dyspepsia. METHODS...

The aetiology of dyspepsia is unknown in the majority of patients. Helicobacter pylori (H pylori) is the cause in a subset of patients. A non invasive test to assess the presence of H pylori is recommended in the management of patients under the age of 50 presenting to a family practitioner with dyspepsia. A urea breath test or a stool antigen test are the most reliable non invasive tests. Erad...

What is dyspepsia? Dyspepsia is not a diagnosis, but rather describes a number of symptoms that are thought to originate in the upper gastrointestinal tract. Dyspepsia is an extremely common disorder in otherwise healthy individuals. Less than half of those with symptoms seek medical care. There is no single, accepted definition for dyspepsia. In this review a broad definition of dyspepsia is u...

background :   vaculating cytotoxic a ( vaca ) gene is one of the multiple helicobacter pylori genotypes that produce a cytotoxin protein (vaca).this gene is a major cause of chronic peptic ulcers and gastric cancer. the aim of this study was to determine the correlation between vaca gene with peptic ulcer disease (pud) and non-ulcer dyspepsia (nud).   methods :    this was a case control study...

OBJECTIVE To determine (a) the advantages and disadvantages of treatment options for the eradication of Helicobacter pylori and (b) whether eradication of H. pylori is indicated in patients with duodenal ulcer, nonucler dyspepsia and gastric cancer. DATA SOURCES A MEDLINE search for articles published in English between January 1983 and December 1992 with the use of MeSH terms Helicobacter py...

OBJECTIVE To determine whether central serotonin receptors are involved in the pathophysiology of non-ulcer dyspepsia. DESIGN Between subjects study of solid phase gastric emptying and prolactin response to buspirone challenge. SUBJECTS 12 patients fulfilling criteria for non-ulcer dyspepsia and 12 age and sex matched controls. MAIN OUTCOME MEASURES Solid phase gastric emptying measured b...

OBJECTIVES No data are currently available on the prevalence and characteristics of functional dyspepsia among cement workers. Given the potential impact of dyspepsia on work performance, whether its prevalence is increased among workers exposed to cement dust was evaluated. METHODS Altogether 420 cement workers were enrolled in the study. According to the individual exposure levels to cement...

Background: Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. Objective: To investigate and compare Tregs and MDSCs in peptic ulcer and gastric cancer. Methods: Patients with dyspepsia were selected and divided into three groups of non-ulcer dyspepsia (NUD, n=22), peptic ulcer disease...