Mutants of Escherichia coli K-12 unable to excise pyrimidine dimers from their deoxyribonucleic acid (DNA) because of a uvr mutation show a higher survival when plated on a minimal salts medium after exposure to ultraviolet radiation than when plated on a complex medium such as nutrient agar containing yeast extract. This response has been called minimal medium recovery (MMR). Recovery of uvr m...

Ultraviolet radiation (UVR) has known adverse effects on the skin and eyes. Practitioners are becoming more aware of the importance of outdoor photoprotection. However, little attention is directed to the exposure of the skin and eyes to UVR through the window glass or sunglasses. The amount of ultraviolet transmission through glass depends mainly on the type of the glass. All types of commerci...

Terrestrial life is dependent on radiant energy from the sun. Solar radiation is largely optical radiation [radiant energy within a broad region of the electromagnetic spectrum that includes ultraviolet (UV), visible (light) and infrared radiation], although both shorter wavelength (ionizing) and longer wavelength (microwaves and radiofrequency) radiation is present. The wavelength of UV radiat...

Organisms living in clear, shallow water are exposed to the damaging wavelengths of solar ultraviolet radiation (UVR) coincident with the longer wavelengths of photosynthetically available radiation (PAR) also necessary for vision. With the general exception of bacteria, taxonomically diverse marine and freshwater organisms have evolved the capacity to synthesize or accumulate UV-absorbing myco...

Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role both in photocarcinogenesis and induction of accelerated skin ageing. Sailors commonly experience a significant number of cutaneous problems, related to the exposure to environmental factors due to their working conditions. Among these factors, sun exposure is able to determine both acute and chronic skin damage, mos...

Since nerve termini on Langerhans cells (LC) contain calcitonin gene-related peptide (CGRP), and since ultraviolet B radiation (UVR) causes CGRP to be released from cutaneous nerve endings, we examined whether CGRP participates in the immune aberrations caused in skin by UVR. First, intradermally injected CGRP, in a dose-dependent manner, reduced LC density and impaired CH induction when hapten...

Background and Objective: Basal cell carcinoma (BCC) is the most widespread malignant skin cancer also common in adults. Although its mortality rate low, incidence increasing, especially Caucasians. Among many risk factors, ultraviolet radiation (UVR) essential factor forming BCC. However, molecular mechanisms leading to transformation are not fully understood. This review provides a comprehens...

AIMS To compare the distribution of eyelid basal cell carcinoma (BCC) with the relative ultraviolet radiation (UVR) exposure to different sites on the eyelids. METHODS The location of BCC on the eyelids was allocated to one of seven regions. The UVR exposure was recorded with a polymer film attached to the eyelids at seven sites in a manikin and in human subjects. RESULTS Localisation of th...

Abstract Although identified as the key environmental driver of common cutaneous melanoma, role ultraviolet radiation (UVR)-induced DNA damage in mucosal melanoma is poorly defined. We analyze 10 melanomas conjunctival origin by whole genome sequencing and our data shows a predominance UVR-associated single base substitution signature 7 (SBS7) majority samples. Our with SBS7 dominance have simi...