minor trauma to the head is common in childhood and does not require any medical or surgical treatment. nevertheless, head injury in infancy and childhood is the single most common cause of death and permanent disability. measurable deficits occur even after mild to moderate head injury but are markedly greater after severe injury. they include impaired cognition, motor impairments, disruption ...

traumatic brain injury (tbi) is an important cause of death and disability in young adults ,and may lead to physical disabilities and long-term cognitive, behavioral psychological and social defects. there is a lack of definite result about the effect of thyroid hormones after traumatic brain injury in the severity and no data about their effect on mortality of the injury. the aim of this study...

objectives we aim to evaluate the role of glibenclamide on the short-term outcome of patients with dai due to moderate to severe tbi. patients and methods in this controlled randomized clinical trial, 40 patients with moderate to severe tbi were assigned to glibenclamide (n = 20) and control (n = 20) groups. six hours after admission the intervention group received 1.25 mg glibenclamide every 1...

BACKGROUND AND PURPOSE Diffusion-weighted magnetic resonance imaging (MRI) has been shown to be particularly effective in detecting early (0 to 4 hours) pathophysiological changes in localized brain regions after cerebral ischemia. The present study sought to establish whether diffusion-weighted MRI would be similarly effective in predicting outcome after traumatic brain injury. METHODS Diffu...

Abstract Spinal cord injury (SCI) often causes severe and permanent disabilities due to the regenerative failure of severed axons. Here we report significant locomotor recovery both hindlimbs after a complete spinal crush. This is achieved by unilateral transduction cortical motoneurons with an AAV expressing hyper-IL-6 (hIL-6), potent designer cytokine stimulating JAK/STAT3 signaling axon rege...

introduction: in iran, thousands of young individuals become victims of head injury annually. head injury can damage neuronal cells which may in turn complicate the recovery of the patients. also, the increase of iron in cerebrospinal fluid (csf) following head injury may contribute to the hypoxic-ischemia brain damage by catalyzing the formation of free radicals (harber-weiss rection). the obj...

over half of all reported traumatic brain injuries are the result of a motor vehicle accident. other then the direct head impact itself, the sheer forces of the accident can cause the brain also to collide against the internal bone of the skull. in fact, when a moving head comes to a quick stop, the brain continues in its movement, striking the interior of the skull. this can cause bruising of ...

in recent years, the usefulness of intracranial pressure (icp) monitoring has been questioned in several reports for traumatic brain injury (tbi) management. therefore the needs of multidisciplinary groups of discussion of neurosurgeons and neurointensivists to update practical applications of icp in severe adult tbi has been advocated in many parts of the world. a consensus conference was held...

emotion regulation difficulties are from the factors that caused the incidents and automobile accidents and work related. this study aimed to comparing emotion regulation difficulties in mild traumatic brain injury (tbi) patients and normal people in kashan.the study was performed on 30 tbi patients referred to shahid beheshti hospital in kashan city and 30 normal people in kashan. tbi patients...

head trauma associated with multiple destructive cognitive symptoms. cognitive destruction leads to impairment in cognitive tasks and cognitive failure. cognitive failures include problems with memory, attention, and operation. this study aimed to comparing cognitive failures in mild traumatic brain injury (tbi) patients and normal people in kashan. the study was performed on 40 tbi patients re...