BACKGROUND The bipolar-unipolar distinction in patients with a major depressive episode is the most important issue related to the diagnosis and treatment of mood disorders, but remains unresolved. This study was undertaken to compare bipolar and unipolar depression on Rorschach testing using the Comprehensive System with reference to healthy Japanese controls. METHODS Patients with bipolar o...

INTRODUCTION Segmental ostial ablation to isolate pulmonary veins is guided by pulmonary vein potentials. The aim of this prospective randomized study was to compare the utility of unipolar plus bipolar electrograms versus only bipolar electrograms as a guide for segmental ablation to isolate the pulmonary veins in patients with atrial fibrillation. METHODS AND RESULTS Isolation of the left s...

BACKGROUND The analysis of eye movements (EM) by eye-tracking has been carried out for several decades to investigate mood regulation, emotional information processing, and psychomotor disturbances in depressive disorders. METHOD A systematic review of all English language PubMed articles using the terms "saccadic eye movements" OR "eye-tracking" AND "depression" OR "bipolar disorders" was co...

Deep brain stimulation of the subthalamic nuclei (STN) is a well established treatment in advanced Parkinson's disease (PD). Based on the clinical efficacy and elicited side-effects, both unipolar and bipolar stimulation modes may be applied. Bipolar stimulation usually produces a more focused and therefore thinner area of tissue activated during stimulation than unipolar stimulation does. The ...

A graph G = (V,E) is a unipolar graph if there exits a partition V = V1 ∪ V2 such that, V1 is a clique and V2 induces the disjoint union of cliques. The complement-closed class of generalized split graphs are those graphs G such that either G or the complement of G is unipolar. Generalized split graphs are a large subclass of perfect graphs. In fact, it has been shown that almost all C5-free (a...

BACKGROUND Selected groups of patients with bipolar and unipolar disorder have an increased mortality rate from suicide and natural causes of death. However, there has been no population-based study of mortality of patients followed up from the onset of the illness. METHODS All patients with a hospital diagnosis of bipolar (n = 15 386) or unipolar (n = 39 182) disorder in Sweden from 1973 to ...

Dysfunctional thought patterns are presumed to underlie cognitive biases in mood disorder patients. However, few studies have compared dysfunctional thought patterns in bipolar manic and unipolar depressed patients. Cognitive schemas and dysfunctional attitudes were evaluated using the cognitive checklist for mania and Dysfunctional Attitudes Scale (DAS) in 34 bipolar manic, 35 unipolar depress...

Background Current classification of unipolar depression reflects the idea that prognosis is essential. However, do DSM-categories of Major Depressive Disorder (MDD), Dysthymic Disorder and Double Depression indeed adequately represent clinically relevant course trajectories of unipolar depression? Our aim was to test DSM-categories (MDD, Dysthymic Disorder and Double Depression) in comparison ...

BACKGROUND Analysis of unipolar voltage maps has been used to detect epicardial scar, but data to define optimal parameters to identify scar remote from the recording site is limited. This study compares the characteristics of electrograms at endocardial sites adjacent to abnormal epicardial sites. METHODS AND RESULTS Data obtained from endocardial and epicardial electroanatomical maps of 31 ...

Background: The identification of differences in seasonality and chronotype may provide useful information regarding unipolar mania as a distinct entity. Therefore, the present study was planned to compare seasonality and chronotype in patients with unipolar mania and bipolar disorder. Method: A cross-sectional study included 60 euthymic outpatients, 30 affected by bipolar affective disorder (b...