a green and convenient méthode for the synthesis of  a variety of xanthene derivatives by condensation reaction between aldehydes and β-naphthol or dimedone in an micellar solution of sodium dodecylphosphonate is described. this method offers several advantages, such as using of a cheap and environmentally benign reaction media, low loadings of sodium dodecylphosphonate as catalyst and easy wor...

nicotine-based ionic liquid has been used as a green catalyst for pyridine-catalyzed huisgen reaction. it promoted addition of dimethylacetylenedicarboxylate to aldehydes or n-tosyl imines leading to efficient synthesis of 2-benzoylfumarates and 1-azadienes respectively under pyridine free odorless ionic liquid conditions. the improved results were obtained in terms of enhanced yields, with min...

d-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1h)-ones under solvent-free conditions. the developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.

an efficient, simple and convenient route is described for the synthesis of biscoumarin (3,3'-(arylmethylene) bis (4-hydroxy-2h-chromen-2-one)) by using of recyclable catalyst tio2@ksf. in this method, we synthesis biscoumarin derivatives via 3multi-component reactions (3mcrs) of two equivalent 4-hydroxycoumarin with one equivalent of aromatic aldehydes using 20 mg nano tio2@ksf as homogen...

The shift of paradigm in combinatorial chemistry, from large compound libraries (of mixtures) on a small scale towards defined compound libraries where each compound is prepared in an individual well, has stimulated the search for alternative separation approaches. The key to a rapid and efficient synthesis is not only the parallel arrangement of reactions, but simple work-up procedures so as t...

The catalytic effect of Zirconia Sulfuric Acid (ZrSA) nanoparticle which is synthesized from thereaction of ZrO with chlorosulfonic acid has been investigated in the synthesis oftetrahydrobenzo[a]xanthene-11-ones by one-pot three-component reaction of β-naphthol,aromatic aldehydes, and dimedone. Different reaction conditions were studied in the presence ofZrSA nanoparticle as catalyst. The resu...

regarding the green chemistry's goals, dicationic magnetic room temperature ionic liquid open up new avenue to introduce an amazing and efficient system for facilitating catalyst recovery in different organic reactions. ability of this dicationic magnetic room temperature ionic liquid catalyst in the one-pot three-components condensation reaction of benzil, aromatic aldehyde, and ammonium aceta...

Improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (Sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. This process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) followed by a halogen-exchange fluorination. This is the first synthesis of Sev...

Improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (Sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. This process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) followed by a halogen-exchange fluorination. This is the first synthesis of Sev...

In the present work, we have developed a mild, efficient, and environmentally benign method for the synthesis of tetrahydrobenzo[b]pyran derivatives via a three-component cyclocondensation of aldehydes, malononitrile and dimedone utilizing ammonium chloride as a simple, easily available and cost effective catalyst under microwave irradiation. This method has several attracting features such as ...