Acute upper gastrointestinal (GI) bleeding is a potentially life-threatening condition requiring accurate, prompt, and appropriate patient evaluation and management. Clinicians of all specialties must know the best practices for preventing and managing upper GI bleeding. This article focuses on assessing and managing adults with acute nonvariceal upper GI bleeding.

BACKGROUND AND STUDY AIMS The small intestine is a potential origin of bleeding in patients with unexplained gastrointestinal tract hemorrhage or iron-deficiency anemia. Most reports on the investigation of these patients describe the use of upper tract enteroscopy. The diagnostic yield of combined upper and lower enteroscopy has not been widely assessed and remains to be clarified. The aim of ...

Acute upper gastrointestinal bleeding (UGIB) is a common indication for upper gastrointestinal endoscopy, with a large audit reporting 14% mortality [1,2]. Although, the gastrointestinal tract is the most common site of the lymphoma, lymphoma is a rare cause of the gastrointestinal bleeding [3]. In this paper, we present a case with non-Hodgkin’s Lymphoma (NHL) resulting in massive gastrointest...

Chlamydia has been detected in the gastrointestinal tracts of both animals and humans. However, the mechanism by which Chlamydia colonizes the gut remains unclear. Chlamydia muridarum is known to spread from the genital to the gastrointestinal tracts hematogenously. The C. muridarum plasmid is a key pathogenic determinant in the mouse upper genital tract although plasmid-deficient C. muridarum ...

After high gastrointestinal tract obstruction the blood fibrin increases rapidly. The change is more marked in animals with obstruction of the cardiac end of the stomach. The rise in fibrin parallels closely the toxemia characteristic of such conditions. These results indicate that liver insufficiency cannot be the cause of death in such obstructions.

Upper gastrointestinal tract malignancies are among the most challenging cancers with regard to response to treatment and prognosis. Cancers of the esophagus, stomach, pancreas, liver, and biliary tree have dismal 5-year survival, and very modest improvements in this rate have been made in recent times. Oncolytic viruses are being developed to address these malignancies, with a focus on high sa...

esophaggogastroduodenoscopy

Nontraumatic hemobilia is a rare cause of upper gastrointestinal hemorrhage in children. In the developing world, infections and inflammation are the two most common causes. Two patients are presented illustrating the diagnostic difficulties. Following recognition of the site of bleeding the surgery was successful in each case. After a review of the literature, a diagnostic workup is proposed.

Heterotopic pancreas is an uncommon developmental anomaly of upper gastrointestinal tract. Heterotopic pancreas tissue is very rarely found in ileum. Intussusception in children is usually idiopathic, but definitive aetiology can be established in 90% of adult cases. We are reporting a case of pancreatic heterotopia presenting as a lead point of ileo-ileal intussusception in a 1year 3month year...