A 9 year old boy with juvenile dermatomyositis developed pulmonary alveolar lipoproteinosis. This previously unreported association was treated successfully by bronchoalveolar lavage.

The amygdala is proposed to process threat-related information in non-human animals. In humans, empirical evidence from lesion studies has provided the strongest evidence for a role in emotional face recognition and social judgement. Here we use a face-in-the-crowd (FITC) task which in healthy control individuals reveals prioritised threat processing, evident in faster serial search for angry c...

Based on studies in rodents, the basolateral amygdala (BLA) is considered a key site for experience-dependent neural plasticity underlying the acquisition of conditioned fear responses. In humans, very few studies exist of subjects with selective amygdala lesions and those studies have only implicated the amygdala more broadly leaving the role of amygdala sub-regions underexplored. We tested a ...

Kirby (1994) has helpfully applied the terminology of signal detection theory to Watson's selection task. We agree with him that it is necessary to bring out the decision theoretic aspects of the selection task (Evans, Over & Manktelow, 1993), and Kirby makes an important contribution by doing this so fully for an abstract version of the task. However, there are problems with both the design of...

A paradigmatic example of an emotional bias in decision making is the framing effect, where the manner in which a choice is posed--as a potential loss or a potential gain--systematically biases an ensuing decision. Two fMRI studies have shown that the activation in the amygdala is modulated by the framing effect. Here, contrary to an expectation based on these studies, we show that two patients...

Memory is defined as being composed of several systems, each with its distinct neural basis. Of these systems the episodic-autobiographical one is considered to have evolved latest and to be most vulnerable to brain damage or stress conditions. Especially structures of the limbic and the prefrontal cortex are regarded as essential for an appropriate processing of autobiographical events. The im...