background helicobacter pylori multiplies and causes infection in human gastric mucosal layer. new approaches have focused on using specific treatments, such as immunotherapy, to limit this infection. urease, as one of the most important virulent and antigenic factors of the bacterium, is a suitable target for this purpose. patients and methods in order to prepare recombinant proteins, the synt...

A nutrition study was conducted to evaluate the growth response of weaned piglets fed diets containing soya beans that had been processed into protein supplements at two different levels of dry matter (DM) and temperature. Four diets contained protein supplements prepared from whole full-fat soya beans equilibrated at 800 or 900 g kgÿ1 DM prior to being heated to 110 or 1258C. An additional die...

BACKGROUND Accuracy of the most frequently used tests for diagnosing Helicobacter pylori infection in patients with upper gastrointestinal bleeding of peptic origin is determined. METHODS Seventy-eight patients with endoscopically-proven upper gastrointestinal bleeding of peptic origin were included. The presence of H. pylori was considered when observed from the histology or, if negative, wh...

In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole (BIA, IC50 2.14 with urease was quantitatively assessed, using UV-Vis, molecular fluorescence, circular dichroism. The results showed that both compounds interact by static fluorescence quenching mechanism non-fluorescent complex formation. ...

Nitrogen (N) management remains a global challenge for the sustainability of diversified farming systems. Field crops are often over-supplied with nitrogen by farmers aiming to high productivity. Although increase rates leads in many instances yields, degree effectiveness use low. Urease and nitrification inhibitors technologies which have been present fertilizers market at least 50 years. Inhi...

The article is devoted to improving the effectiveness of technological impact on soy in order remove anti – nutritional substances from it-trypsin inhibitors and urease enzymes. This achieved by intensifying mass transfer during extraction ultrasonic pulsating micro-flows cavitation with formation oxidizer hydrogen peroxide H2O2. developed technical means provide high inactivation rates increas...

Background: The growing spread of drug resistance in Helicobacter pylori has caused concern. Urease is one the most important enzymes associated with H. activity. Oxadiazoles have a wide range inhibitory activities. aim this study was to investigate new oxadiazole compounds as urease inhibitors pylori. Methods: synthesized were reused ligands previous study, and initial structure optimized by M...