OBJECTIVE To evaluate the efficacy and safety of vaginal misoprostol for cervical priming before diagnostic outpatient hysteroscopy (OH) without anesthesia. DESIGN Double-blind randomized controlled trial. SETTING University teaching hospital. PATIENT(S) One hundred fifty patients requiring diagnostic OH for investigation of infertility or abnormal uterine bleeding in the reproductive age...

Aim: To compare the sublingual and vaginal routes of misoprostol in termination of first trimester missed abortion. Methodology: The study was carried out in the Obstetrics & Gynecology unit-II of Bahawal Victoria Hospital Bahawalpur, Pakistan, having yearly turnover > 3000 indoor patients. Results: In vaginal misoprostol group 66.7% cases completely aborted while in sublingual group 73.3% expe...

Misoprostol in oral or vaginal form is an established method of labour induction worldwide. Its use after previous caesarean section is associated with a high rate of uterine rupture; according to international guidelines it is therefore contraindicated in this setting. However the evidence base for this recommendation comprises case reports, one randomised trial that was discontinued premature...

Objective: To compare the effect of sublingual versus vaginal misoprostol on preoperative cervical priming in first trimester abortion. Material and methods: One hundred women seeking first trimester abortion were randomized into either sublingual or vaginal groups of 50 each. They were given 400 μg misoprostol via sublingual or vaginal route for cervical priming three hours before the procedur...

OBJECTIVE Comparing sublingual and vaginal misoprostol in second trimester pregnancy termination. MATERIALS AND METHODS In this study 268 women at 12-24 weeks of gestation candidate for pregnancy termination were enrolled. Women were randomly divided in two groups. The first group received 400 µg sublingual misoprostol and vaginal placebo and the second group received 400 µg vaginal misoprost...

background: termination of pregnancy in the second trimester using prostaglandins has been shown to be safe and effective. misoprostol has multiple routes of administration; oral, vaginal, buccal, rectal and sublingual.objective: the study aims to compare the efficacy and safety of intrauterine extra-amniotic and vaginal misoprostol in a dose of 200 microgram every 4 hours for the termination o...

OBJECTIVE To compare the safety and efficacy of misoprostol with that of dinoprostone for the induction of labour at term, or near term. DESIGN Three hundred and ninety-six women with term pregnancies were randomised to receive either oral or vaginal misoprostol, or dinoprostone. Women who had had a previous caesarean section (CS) or those with a malpresentation or who were parity > or = 5, w...

objective: comparing sublingual and vaginal misoprostol in second trimester pregnancy termination. materials and methods: in this study 268 women at 12-24 weeks of gestation candidate for pregnancy termination were enrolled. women were randomly divided in two groups. the first group received 400 µg sublingual misoprostol and vaginal placebo and the second group received 400 µg vaginal misoprost...

BACKGROUND The induction of full-term labour in women with a live fetus remains a major challenge in modern obstetrics. OBJECTIVES To determine, using the best level of evidence available, the efficacy and safety of sublingual administration of misoprostol compared with vaginal misoprostol in the third trimester of pregnancy for the induction of labour, according to initial doses, in women wi...