Bacterial vaginosis is a highly prevalent and poorly understood polymicrobial disorder of the vaginal microbiota, with significant adverse sequelae. Gardnerella vaginalis predominates in bacterial vaginosis. Biofilms of G. vaginalis are present in human infections and are implicated in persistent disease, treatment failure, and transmission. Here we demonstrate that G. vaginalis biofilms contai...

A cross-sectional study was conducted during May-December 2000 among pregnant women attending an urban maternal and childcare-delivery unit in Dhaka, Bangladesh, to assess the prevalence of bacterial vaginosis, Trichomonas vaginalis, and syphilis. All pregnant women at 16-24 weeks gestation attending the clinic for antenatal check-up irrespective of symptoms were enrolled. Sociodemographic info...

Esse estudo teve como objetivo identificar as características clínicas e morfológicas de vaginose citolítica. Trata-se uma scoping review (análise escopo), realizada em três bases dados, com os descritores “Cytolytic vaginosis”, “Bacterial, vaginosis” “Vaginosis”. Dentre critérios elegibilidade, foram incluídos artigos publicados periódicos indexados na área da saúde, disponíveis forma online í...

Bacterial vaginosis, trichomoniasis, and genital candidiasis are considered the main etiologies of vulvovaginitis. Few studies estimate the prevalence of vulvovaginitis among adolescents, especially in Brazil. This study aimed to determine the prevalence and main risk factors associated with bacterial vaginosis and genital infection by C. albicans and Trichomonas vaginalis among a group of adol...

Bacterial vaginosis has been appreciated as a unique clinical entity for well over 50 years. Its essential manifestations are well established: a loss of the normal bacterial population of the vagina and their replacement by other species. Investigations into this condition have led to a better understanding of its prevalence and epidemiology. Microbiologic and biochemical studies have exposed ...

Asymptomatic maternal genital tract infection during pregnancy, particularly bacterial vaginosis, has been consistently associated with preterm birth. In response to this evidence, the Maternal-Fetal Medicine Units Network (MFMU) designed and conducted 2 large randomized, placebo-controlled clinical trials of metronidazole treatment of asymptomatic pregnant women with bacterial vaginosis or tri...

OBJECTIVE Conventional diagnosis of bacterial vaginosis contains some controversial points. To understand accurately the relationship between clinical stages and the microbiotas, the intravaginal microbial flora was analyzed by the clone library method. STUDY DESIGN Vaginal fluid samples from 31 patients were examined. Lactobacillary grade, Nugent score, culture-based method, and clone librar...

Anaerobic (bacterial) vaginosis is a vaginal syndrome of unknown aetiology in which women complain of a fishy smelling vaginal discharge and the normal lactobacillus dominated vaginal flora is replaced by a profound overgrowth of Gardnerella vaginalis, Mycoplasma hominis, and mixed anaerobes, particularly Prevotella, Porphyromonas, and Mobiluncus species. The vaginal pH is elevated (usually pH ...

BACKGROUND Preterm birth before 37 weeks' gestation is associated with 70% of perinatal morbidity and nearly half of long-term neurological morbidity. Hospital-based studies have shown that bacterial vaginosis is associated with preterm birth. AIM To estimate the relative risk of preterm birth in women with and without bacterial vaginosis, detected by self-administered vaginal swab at < 10 we...

OBJECTIVE To evaluate the efficacy and safety of a 3 day course of 2% clindamycin cream in the treatment of bacterial vaginosis. DESIGN A prospective, randomised, double blind, placebo controlled study. SETTING Department of Genitourinary Medicine, Royal Liverpool University Hospital. SUBJECTS 55 female patients aged 18 years and over, and premenopausal, who spontaneously or after questio...